mid term prep Flashcards
1
Q
What are basic numerical values for alpha helix
A
3.6 residues per turn
5.4 angstrum rise per turn
stbilised by H bond between carbonyl O n and NH n+4
2
Q
Why are glycine + proline helix breakers
A
Glycine = too flexable for the structure
Protline = cannot form an H-bond with N-termin, to ridged to form appropriate phi bond
3
Q
What is the most common amino acid in beta turns
A
Proline in the second location -> naturally bends back on itself as side chain binds to amino group forming curve
4
Q
What is a chaperonin
A
a bin like large chaperone made from two parts GroHS, GrosEL
5
Q
Wat is missfolding of amyloid protein predicted to be associated with
A
type 2 Diabetes or/and altzhimers
6
Q
A
