Nutritional Diseases Flashcards
What is nutrition?
The process by which humans obtain and use substances from food (nutrients) to maintain structural and functional integrity
What is optimal nutrition?
Food secure individuals with an adequate balanced diet
Healthy, normal development and high quality of life
What is undernutrition (hunger)?
Food insecure Depletion of energy Poverty Ignorance Political unstable environment Increased physical and mental development Increased infections
What is malnutrition?
Serious depletion of nutrients (other than energy)
Similar to undernutrition but increased burden
What is starvation?
Involuntary lack of food
What is fasting?
Voluntary lack of food
What is famine?
Severe food shortage in the community
What are the issues in nutrition?
Nutrient-gene interactions Phytochemicals Childhood obesity Requirements of an ageing population Food security for everyone Food safety
What are the factors affecting energy intake?
Appetite
Hunger
What is vitamin D?
Hormone-cholesterol based
Formed following exposure to UV
What percentage of bone is replaced each year?
5-10%
What is the purpose of calcitrophic hormones?
Regulate bone formation and resorption
What are some examples of calcitrophic hormones?
Parathyroid hormone Vitamin D Sex steroids Glucocorticoids Growth hormone Insulin-like growth factor
What are the main bone diseases?
Osteoporosis
Rickets and osteomalacia
What is osteoporosis?
Systemic disease of the skeleton where there is low bone mass and an impairment of the microarcitecture of bone
For which cancers is there evidence of a link with vitamin D deficiency?
Colo-rectal
Breast
What are the mechanisms of vitamin D deficiency being linked to cancer?
Influences DNA of cancer cells
Promotes cellular arrest
Curbs multiplication of cancer cells
Inhibits cancer from spreading
Which components of heart disease is there links with vitamin D deficiency?
Hypertension
Inflammation
Blood lipids
What are the mechanisms of vitamin D deficiency being linked to heart disease?
Activates mechanism that boosts blood pressure
Stimulates parathyroid hormone which increases inflammation and insulin resistance
What is good vitamin D status linked with?
Lower risk of multiple sclerosis
Fewer symptoms in MS patients
Fewer symptoms in patients with rheumatoid athritis