Iron Deficiency & Disease Flashcards
1
Q
What are the characteristics of erythrocytes?
A
Biconcave disk
120 day lifespan
No organelles
2
Q
What is the function of haemoglobin?
A
To carry gases around the body
Bind to multiple gases
Form carboxyl haem
3
Q
Where does a red blood cell get its energy from?
A
Embden-Meyerhof Glycolyic pathway
4
Q
What is microcytic hypochromic anaemia?
A
Nutritional deficiency of iron
Iron overload
5
Q
Why is unbound iron toxic?
A
It causes free radical formation
6
Q
Where is iron absorbed into the body?
A
Duodenum
7
Q
What is anaemia?
A
Lowering of haemoglobin levels
8
Q
What molecule does iron bind to, to be transferred to erythrocytes?
A
Transferrin
9
Q
What is the aetiology of anaemia?
A
Decreased proliferation of RBC
Impaired maturation of RBC
Loss of blood
10
Q
What are the stages of erythrocyte development?
A
Stem cell Early erythroblast Intermediate erythroblast Late erythroblast Reticulocyte Mature RBC
