Nutrition and diet Flashcards
How can nutrition affect tooth development ?
affect in utero tooth development
affect posteruptive tooth development
affect caries and periodontal disease
What are the macronutrients ?
fat
carbohydrate
protein
What is the purpose of the macronutrients ?
provide energy
What are the micronutrients ?
vitamins minerals and trace elemnts
What can energy be measured in ?
kJ or kcal
How many kcal per fat gram ?
9 kcal per gram of fat
How many kcal per carbohydrate ?
4 kcal
How many kcal per protein gram ?
4 kcal
How many kcal per gram of alcohol ?
7 kcal
How many kJ in one kcal ?
i kcal-4.18 kJ
What is EAR ?
estimated average requirment
total dietary intake prediced to maintain energy
What happens to excess energy ?
stored as fat
What is EAR required for ?
temperature maintenance
breathing
heartbeat
brain function
What does EAR maintain ?
BMR
basic metabolic rate
When is BMR altered ?
body builders
pregnant
What is a healthy BMI ?
18.5 and 24.9
What is EAR based on ?
body size and composition
gender
age
activity level
What 2 things link EAR in an equation ?
EAR= BMR x PAL
What is the EAR of adult men ?
2772 kcL
What is the EAR of 1 year old girls ?
646 kcal
What is the EAR of 1 year boys ?
718
What is the EAR of adult women ?
2079 kcal
What are fats composed of ?
glycerol and fatty acids
What are types of fatty acids ?
saturated and monounsaturated and polyunsaturated
What are saturated fatty acids ?
no double bonds
only single carbon carbon bond
Where can you find saturated fatty acids ?
animal and dairy fats
Where can you find MUFA ?
seeds and nuts
Where can you find PUFA ?
oils
What are the functions of dietary fats ?
make lipid bilayer energy release precursors of prostaglandins precursor of cholesterol absorption of ADEK
What are essential fatty acids ?
not made in the body
must come from diet
What is cholesterol needed for ?
fat absorption via chylomicrons
What are the essential fatty acids ?
alpha lionlenic
linoleic
Where can you find lionleic and linolenic fatty acids ?
plant oils
What are omega 3 fatty acids ?
3 carbon double bonds before the methyl end of the chain
Give an example of an omega 3 fatty acid ?
lionoleic fatty acid
What odes alpha linolenic acid do ?
converts into EPA and DHA
What is EPA ?
EICOSAPENTANOIC ACID
What is DHA ?
docosahexanoic acid
What is the purpose of DHA and EPA ?
form prostaglandins
decrease cardiovascular risk
prevent periodontal disease
reduce platelet aggregation and hence thromboembolic episodes
What is a cis fatty acid ?
hydrogen atoms orinetated in one direaction
What is a trans fatty acid ?
hydrogen atoms orientated in different direction
What do hydrogenated oils contain ?
trans fatty acids
cheaper than animal fats
What is trans fat intake strongly associated with ?
colon cancer
cardiovascualr disease
What does accumulation of cholesterol rich lipid lead to an increase in ?
increase cardiovascular disease risk
Which is the bad type of cholesterol ?
LDL
What can saturated fat increase ?
LDL
What do trans fatty acids to ?
increase LDL
decrease HDL
What does dietary cholesterol increase ?
increases LDL
How can we substitute saturated fat ?
with PUFA- secreases cholesterol
What do plant stanols and sterols do ?
prevent cholesterol absorption
lower LDL cholesterol
What is a commercial plant stanol ?
benecol
What can also lower cholesterol ?
oat fibre
soya protein
How do oat fibres reduce cholesterol absorption ?
beta glucans in oat fibres bind to cholesterol and sequester it
What is obesity associated with ?
cancer
What is high animal fat intake associated with ?
bowel
pancreas
prostate
cancer
How much of the total dietary intake should come from fat ?
less than 35%
less than 5% from saturated fat
What are the types of carbohydrates ?
starch
sugars
fibre
oligosaccharides
What is starch ?
amylose and amylopectin
bread, pasta. potatoes
What are the types of sugars ?
monosaccharidea
disaccharides
What are sugar alcohols ?
xylitol
sugar substitutes and sweetners
How much kcal do sugars produce ?
4 kcal per gra
What is excess energy from sugar stored as ?
glycogen and fat
What are sugars used for in the body ?
glycoproteins - albulin
GAGs- hyaluronic acid
proteoglycans
What can high sugar intake lead to ?
obesity
cardiovascular disease
diabetes
What are oligosaccharides ?
2 or more sugar molecules bonded
What is fibre?
non glycaemic carbohydrates
What are the classifications of fibre ?
NSP
resistant starch
resistant oligosaccharide
What is NSP ?
cellulose
pectine
mucilages
How is NSP digested ?
not in the digestive tract
passes to the colon and undergoes microbial anaeroic fementation
adds to stool bulk and stimulate peristalsis
What is insoluble NSP ?
adds to stool mass
increases satiety- good for weight loss
What is resistant starch ?
starch not digested because enclosed in cells
green bananas
What is resistant oligosaccharide ?
encourage growth of bifodobacterium and lactobacillus so can increase caries risk
What are maltodextrins and glucose syrups ?
made from starch hydrolysis
can be found in soya infant formula
increase cariogenic risk
What is the recommended intake of free sugars ?
5% of all dietary intake
How much sugar intake in children 11+ ?
30 g sugar
What are the functions of dietary proteins ?
muscle and tissue maintenance
hormones and enzymes
What are animal sources of proteins ?
meat dairy and fish
What are the vegetable protein sources ?
pulses
nutes
What is the nitrogen balance ?
the balance determines requirements for proteins
amount of nitrogen we intake should equal amount excreted
What is a positive nitrogen balance ?
amount excreted in less than amount taken in
growth and pregnancy
What is a negative nitrogen balance ?
amount excreted is more than amount uptaken
in starvation
How much nitrogen is in 6.25g of protein ?
1 g of N
How much protein do people require ?
0.75 kg to 1.g kg per kg of weight
bascially 1 g for every kilo
How much of total dietary intake is protein ?
12%
What are the 3 types of protein deficiency syndromes ?
marasmus
kwashiorkor
NOMA
What is marasmus ?
protein-energy malnutrition
severe muscle wasting
decreased insulin:glucagon
muscle proteins used in liver to make albumin - prevents oedema
What is kwashikor ?
protein deficiecny
high insulin: glucagon
reduced amino acids for albumin synthesis causes oedema
What is NOMA ?
malnorushment
ulceration and stomatitis
of upper gum. maxilla and cheeks
What is beta carotene ?
a yellow pigment antioxidant that is converted to vitamin A
found in yellow vegetables
What are sources of vitamin A ?
cheese eggs milk eggs yoghurt leafy vegetables
What are the fucntions of the vitamin A ?
sight- retinol production T cell differentiation Maintenance of healthy skin regulates gene expression anti oxidant
What is the recommended intake for vitamin A ?
750 micrograms for men
650 micrograms for women
What are signs of vit A deficiency ?
eczema
night blindness
infertility
What are oral healthy symptoms in deficiency ?
increased keratin formation- blocks saliva ducts leading to xerostomia
enamel hypoplasia
delayed tooth eruption
What are sources of thiamine ?
meat
bread
What is thiamine (B1) used for ?
metabolic pathways to convert carbohydrates to ATP
What are signs of thiamine deficiency ?
weight loss
anorexia
muscle weakness
beri beri disease
What are sources of riboflavin (B2) ?
animal products
What is the function of B2 ?
metabolism of fats
conezymes
conversion of carbs to ATP
What are signs of deficiecny of riboflavin ?
anaemia
cataracts
skin disorders
What are oral symptoms of thiamine deficnecny ?
thiamine deficinecy cna cause vomiting effecting enamel
What are oral symptoms of riboflavin deficiency ?
ulceration
angular cheilitis
mucosal inflammation
What are sources of folate ?
green veg
nuts
beans and dairy
What is the fucntion of folic acid ?
neural tube closuure
What can happen with folic acid deficiency ?
failure of neural tube to close
leads to anencephaly
What are sources of B12 ?
animal products
What are the fucntions of B12 ?
coenzyme
DNA and RNA synthesis
What does folic acid and B12 deficinecy lead to ?
megaloblastic anaemia
What are the oral symptoms of B12 and folate deficinecy ?
lack of keratinisation
pale mucosa
angular cheilitis
What are sources of vitamin C ?
oranges
red peppers
brocolli
supplements
What are functions of vitamin C ?
collagen synthesis
cartialge and bone
wound healing and scar formation
antioxidant
What are symptoms of vitamin C deficiency ?
painful joints
osteoporosis
scurvy
dry skin and hair
What are the oral symptoms of vitamin C deficiency ?
swollen , erethematous gingiva
PDL breakdown as it made of collagen
antioxidant- reduce ROS in inflammation
What are the fat soluble vitamins ?
A D E K
What are sources of vitamin K ?
green leafy veg nuts seeds meat dairy
What are the fucntions of vitamin K ?
needed in acitivation of vitamin K dependent clotting factors
2,7, 9 and 10
Which medication should you not prescribe to someone with folic acid deficiency ?
sulfonamides
trimethoprim
What can vitamin K deficiency lead to ?
haemorhage
excessive bleeding
easy bruising
What are oral symptoms of vitamin K deficiency ?
osteocalcin regulates mineralisation and is vit K dependent
What are the sources of nicotinic acid (B3) ?
meat
fish
wheat
fortified cereals
What are the functions of vitamin B3 ?
protein and fat metabolism
inhibit LDL production
precursor of enzymes- NAD
What are signs of nicotinic acid deficinency ?
pellagra- thick scaly rash
What are oral symptoms of nicotnic acid deficinecy ?
atrophic glossitis
atrophy of filliform anf fungifomr papillae
angular stomatitis
What are sources of vitamin D ?
oily fish
red meat
sunlight
What is the function of vitamin d ?
increeases blood calcium via absorption
1,25 DHCC converted from D to allow bone resorption and GIT abosrbance
What are the signs of vitamin D deficiency ?
rickets
weak immune system- innate immunity
What are the oral symptoms needs of vitamin D ?
allows calcium absorption
hydroxyapatite formation
What are sources of calcium ?
dairy
green veg
tofu
What are the functions of calcium ?
muscle contraction
blood clotting
nerve signalling
bone and tooth formation
What are the signs of calcium deficiency ?
muscle cramps
brittle fingernails
osteoporosis
insufficinet blood clotting
What are sources of magnesium ?
dark chocolate
avocado
legumes
What are the functions of magnesium ?
co factor for muscle contraction
glycaemic control
ionic transport
What are the symptoms of magnesium deficiency ?
muscle cramps
nausea
seizures
decreased apatite
What are the oral symptoms of magnesium deficiency ?
anti inflammatory- lack of can lead to gingival inflammation
can lead to reduced calcium absorption
What are the sources of iron ?
liver
beans
fortified cerelas
dark green veg
What is the function of iron ?
haemoglobin formation
What are the symptoms of iron deficiency ?
tiredness
paleness
shortness of breath
dizziness
What are the oral symptoms of iron deficiency ?
pale tongue
angular cheilitis
What are sources of zinc ?
oysters
red meat
phyates can bind to zinc and prevent absorption- soak beans
What are the functions of zinc ?
cell division
cell growth
wound healing
T cell development
What are the signs of zinc deficiency ?
immune problems
loss of smell and taste
lethargy
acne
What is the oral significance of zinc ?
found in saliva to inhibit plaque growth
inhibits bacterial metabolism
What are dietary reference values ?
given for food, energy and nutrients in the UK
amount of nutrient needed for different groups like age and gender
What are dietary reference values given for ?
carbohydrates- free sugars and fibre
protein -
fat- saturated and trans
What are DRVs based on ?
popualtions not individulas
What is the RNI ?
reference nutrient intake
amount of nutrient enough to satisfy 97.5% of population
Where is RNI on a normal distribution graph ?
near the end
What is the estimated average requirement ?
EAR
estimate of the average requirement of energy or a specific nutrient
approximately 50% of population will need less energy and 50% will need more
What is RNI used for ?
reference amount for population groups
What is EAR used for ?
energy
What is LRNI used for ?
nutritional inadequacy
What is the LRNI ?
lower reference nutrient intake
amount of nutrient enough for only a small number of people
they have low requirements- 2.5%
majority of population will need more
How much should fat constitute of total energy intake ?
35%
less than 10% saturated
less than 2% trans fat
How much should free sugars constitute total energy intake ?
5%
How much should protein constitute total energy intake ?
12-15%
How much sugar should 11+ have ?
no more than 30g
How much sugar should 7-10 years ?
no more than 24g
How much sugar should 4-6 years have ?
no more than 19g
What is the eatwell guide ?
guide to proportion of each nutrient needed daily
What does eatwell guide recommend for fruit and veg ?
5 a day
What are the portions of fish required from the eatwell guide ?
2 portions a weel
1 should be oily
What are portions of red meat needed according to EP ?
limit to less than 70g
How much fluid should be taken according to EP ?
6/8 glasses a day
Which starchy foods are needed in EP ?
bread rice potatoes pasta wholegrain provide fibre, protein, B vtamins and vitamin E
What is the recommendend milk and dairy intake ?
moderately
choose low fat varieties
What are the protein requirements according to EP ?
eat moderate amounts
choose low fat- remove skin from chicken
eggs and fish in this group
What is enamel hypoplasia ?
structural defect in enamel
enamel is present and well mineralised but deficient in amount
What are the manifestations of enamel hypoplasia ?
alteration of shape
pits and grooves
What is enamel hypomineralisation ?
defects in which enamel matrix is present
reduced mineral content
enamel opacities and chips
What are some of the manifestations of hypomineralisation ?
enamel chips
white and brown marks softer
What is one cause of developmental enamel defects ?
nutritional deficiency
What is the problem with enamel defects ?
can get stained
carious risk
What is manifestations of enamel hypoplasia ?
pits and grooves
What are some of the nutrient deficiencies that can lead to enamel hypoplasia ?
vitamin A vitamin D hypocalcaemia PEM LBW
What are the causes of LBW ?
placental insufficinecy
maternal undernutrition
What are the conclusions in the guatemalen rats study ?
providing a protein supplement does not reduce the caries incidence.
What is the effect of protein insufficiency in mothers diet ?
poor quality milk
increased dental caries
provide the protein in utero nd differneces are abolished
differences not abolished when given post birth
What does protein deficiency cause ?
salivary gland atrophy
xerostomia leads to rampant caries
What does vitamin D dependent caries lead to ?
low calcium
low phosphate
hypoplasia
What does hypophosphataemia lead to ?
normal calcium
low phosphate
no hypoplasia
What does hypoparathyroidism lead to ?
low calcium
high phosphate
hypoplasia
Why is hypocalcaemia common in undernourished children ?
diarrhoea induced
What is vitamin A deficiency linked to ?
PEM
linked to defects
What is the rat vitamin A deficiency experiment ?
vitamin A deficient rates given a highly cariogenic diet had higher caries
What does vitamin A deficinecy lead to ?
salivary gland hypotrophy
poor quality saliva
What happened to dogs on a vitamin D deficient diet ?
poorly aligned teeth
delayed eruption
delayed development
enamel and dentine defects
What can be concluded from the may mellanby experiment ?
all teeth with hypoplasia has caries
vitamin D is a factor responsible for caries
What happened when children were given a vitamin D supplement ?
reduced inititiation and spread of caries
What happened in world war II ?
improvement in childrens teeth due to reduction in sugar cheap milk (calcium and vitamin d) Cod liver oil vitamin A and D added to margarine calcium carbontae added to flour
What do the vitamin D studies in india conclude ?
gross enamel hypoplasia due to diarrhoea indiced hypocalcaemia
mild enamel hypolasia is same as UK as the sunshine compensates for it
What does vitamin D do with caries ?
may lead to developmental defects
which can lead to more dental caries
low certainty conclusions that it may decrease dental caries incidence
What is the PHE advice for vitamin D ?
adults and children over the age of 1 should hvae 10 mcg
equivalent of 5 sardines
What can lead to high caries rates in developing countries ?
poor diet
high sugars
What does under nutrition lead to ?
lack of PE results in developmental defects
making tooth caries prone
salivary gland atrophy
delays eruption
What does dental fluorosis lead to ?
opacities
mottling
hypomineralisation
What does excess fluoride ingestion lead to ?
alters the rate at which amelogenins are removed enzymatically
alter the action of protease- decrease availability of free calcium
What are the manifestations of fluorosis ?
hypomineralised
alteresd optical properties
opaque
What does the dean research tell us ?
continued use of water- 1 ppm - 10%
continued use of water at 1.7 ppm- 40%