Nutrient Digestion and Absorption (Fat and Vitamins) Flashcards

1
Q

What is lipase?

A

Water soluble enzyme

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2
Q

What are the components of triglycerides?

A

1 glycerol : 3 fatty acids

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3
Q

What is emulsification?

A

Division of large lipid droplets into smaller droplets, speeding up digestion

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4
Q

What are the components of micelles?

A

Bile salt + fatty acids + phospholipids + monogylcerides

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5
Q

What is the orientation of molecules within the micelle?

A

Polar portions at micelle surface, non-polar portions from micelle core

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6
Q

What occurs when micelles breakdown?

A

Free fatty acids and monoglycerides are released into solution and diffuse across the plasma membrane of absorbing cells

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7
Q

What occurs after the free molecules from the micelle enter cells?

A

Enter smooth endoplasmic reticulum and are reformed into triglycerides
Processed through golgi apparatus
Exocytosed into extracellular fluid

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8
Q

What are extracellular fat droplets called?

A

Chylomicrons

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9
Q

What do chylomicrons contain?

A

Phospholipids
Cholesterol
Fat soluble vitamins

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10
Q

How are chylomicrons transported?

A

Lacteals between endothelial cells

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11
Q

What are the fat soluble vitamins?

A

Vitamins A, D, E, K

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12
Q

What are the water soluble vitamins?

A

Vitamins B, C and folic acid

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13
Q

What is caused by B12 deficiency?

A

Pernicious anaemia

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14
Q

How is iron transported?

A

Moves across brush border membrane into duodenal enterocytes

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15
Q

How is unbound iron transported?

A

Moves through serial membrane into the blood

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16
Q

What is the cause if hyperaemia?

A

Increased ferritin levels, more iron bound in enterocytes

17
Q

What is the cause of anaemia?

A

Decreased ferritin levels, more iron released to the blood

18
Q

Why is it important that iron is bound to ferritin?

A

Iron can react with oxygen, creating free radicals