Gastric secretion Flashcards
What role does the oblique muscle have in peristalsis?
Squeezing twist
What is the intrinsic factor a requirement for?
Vitamin B12 absorption
What part of the stomach is gastrin secreted from?
Antrum
How does the stomach become acidic?
HCO3- taken into the blood and chloride leaves the blood and passes into the stomach lumen
Potassium hydrogen pumps pulls hydrogen into the lumen
Water is also drawn into the lumen between the tight junctions
What is the role of the gastric mucus?
Protects mucosal surface from mechanical injury
Protects against gastric acid corrosion and pepsin digestion
What secretes pepsinogen?
Chief cells
At what pH is pepsin inactivated?
pH 7
What does zymogen storage prevent?
Cellular digestion
What are enterogastrones?
Hormones released from gland cells in duodenal mucosa
When are enterogastones released?
In response to acid, hypertonic solutions, fatty acids in duodenum
What are the effects of enterograstone secretion?
Inhibit gastric acid secretion
Reduce gastric emptying
What are the 2 main enterogastrones?
Secretin
Cholecystokinin (CKK)
What is the cause of vagal stimulation of gastric acid secretion?
G cells secrete gastrin
Histamine secretes gastrin
