Liver Symposium Flashcards
What type of hepatitis cause enteric viruses?
Hepatitis A
Hepatitis E
What type of hepatitis cause parenteral viruses?
Hepatitis D
Hepatitis C
Hepatitis D
What type of hepatitis cause chronic disease?
Hepatitis B
Hepatitis C
Hepatitis D
How is hepatitis A transmitted?
Faecal-oral
Sexual
Blood
Who gets immunisation fro Hepatitis A?
Travellers
Occupational exposure
Chronic liver disease patients
Men who have sex with men (MSM)
How is hepatitis B transmitted?
Vertical (mother to child)
Sexual
What is the make up of the hepatitis B vaccine?
Only contains surface antigens
What are the drugs used to treat hepatitis C?
Sofobuvir
Ledipasvir
What type of virus is hepatitis D?
RNA
Resistant to treatment and usually coinfects with HBV
What is the treatment for hepatitis E?
No specific treatment or effective vaccine and is self limiting
What are the different types of fatty liver disease?
Non alcoholic steatosis
Non alcoholic steatohepatitis
What are the risk factors for fatty liver disease`?
Diabetes Obesity Hypertension Hpercholesterolaemia Age Ethnicity (hispanic)
How do you diagnose fatty liver disease?
Biochemical tests (AST/ALT ratio) Ultrasound MRI/CT Liver biopsy Cytokeratin-18 Scoring system used
How do you treat fatty liver disease?
Diet and weight reduction Exercise Insulin sensitisers Vitamin E Weight reduction surgery
What is autoimmune hepatitis?
Elevated IgG
How is autoimmune hepatitis treated?
Long term azathioprine
What are the clinical signs of primary biliary cholangitis?
IgM elevated
Anti-mitochondrial antibody positive
What is the treatment for primary biliary cholangitis?
UDCA treatment
What are the clinical signs of primary sclerosing cholangitis?
pANCA positive
intra and extra hepatic bile ducts involvement
MRCP test
How do you treat primary sclerosing cholangitis?
Biliary stents
Who are the appropriate liver transplant candidates?
Hepatocellular carcinoma
Acute liver failure
Genetic diseases
Chronic liver disease with poor predicted survival and associated poor QOL
What are the contraindications for liver transplant?
Malignancy
Active and uncontrolled infection
Active substance or alcohol abuse
Severe cardiopulmonary or other comorbid conditions
What is the post operative liver transplant treatment?
ICU
Prophylactic antibiotics and anti fungal drugs
Anti rejection drugs (steroids, azathioprine, tacrolimus)
What dose CAGE stand for?
Cut down
Annoyed by criticism of your drinking
Guilty about your drinking
Eyeopener