Nucleic aid synthesis inhibitors Flashcards
1
Q
Drug type consist of:
Nalidixic acid
Ciprofloxacin
Levofloxacin
gemifloxacin
Moxifloxacin
Norfloxacin
Ofloxacin
Pefloxaicin
(ALL FLOXACIN)
A
Fluoroquinolones / Quinolones
2
Q
What is the derivation for Fluoroquinolones / Quinolones?
A
Synthetic
3
Q
Inhibit DNA synthesis by binding DNA gyrase and Topoisomerase IV
A
Fluoroquinolones / Quinolones
4
Q
Drug type for rifampin, rifapentine, Rifaximin, rifabutin
A
Rifamycin
5
Q
What is the bacteria derive for rifamycin?
A
Streptomyces mediterranei
6
Q
DNA dependent RNA polymerase?
A
Rifamycin
7
Q
Rifampic is usually use in combination for the treatment of Mycobacterium
A
Isoniazid and pyrazinamide