Nucleic aid synthesis inhibitors Flashcards

1
Q

Drug type consist of:
Nalidixic acid
Ciprofloxacin
Levofloxacin
gemifloxacin
Moxifloxacin
Norfloxacin
Ofloxacin
Pefloxaicin

(ALL FLOXACIN)

A

Fluoroquinolones / Quinolones

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2
Q

What is the derivation for Fluoroquinolones / Quinolones?

A

Synthetic

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3
Q

Inhibit DNA synthesis by binding DNA gyrase and Topoisomerase IV

A

Fluoroquinolones / Quinolones

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4
Q

Drug type for rifampin, rifapentine, Rifaximin, rifabutin

A

Rifamycin

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5
Q

What is the bacteria derive for rifamycin?

A

Streptomyces mediterranei

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6
Q

DNA dependent RNA polymerase?

A

Rifamycin

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7
Q

Rifampic is usually use in combination for the treatment of Mycobacterium

A

Isoniazid and pyrazinamide

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