Metabolic process inhibitors Flashcards
What are the enzymes for metabolic processes inhibitors that are involved in the synthesis of folate for the production of _______?
Dihydrofolate reductase and Dihydopteroate synthase
Nucleic acid (Blank part)
What are the Drugs for metabolic processes inhibitors?
Sulfonamides
Trimethoprim
Nitrofurans
What is the drug name for sulfonamides and trimethoprim?
Trimethoprim-sulfamethoxazole
What is the drug name for Nitrofurans?
nitrofurantoin
All metabolic processes inhibitor drugs are derive from?
Synthetic
Disrupt the folic acid pathway by binding to dihydropteroate to dyhydropteroate synthase
Sulfonamides
Disrupt the folic acid pathway by binding to dihydropteroate to Dihydrofolate reductase
Trimethoprim
Exact mechanisms uncertain but probable bacterial enzyme targets and direct DNA damage
Nitrofurans
Treatment for UTI only?
Nitrofurans