Metabolic process inhibitors Flashcards

1
Q

What are the enzymes for metabolic processes inhibitors that are involved in the synthesis of folate for the production of _______?

A

Dihydrofolate reductase and Dihydopteroate synthase

Nucleic acid (Blank part)

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2
Q

What are the Drugs for metabolic processes inhibitors?

A

Sulfonamides
Trimethoprim
Nitrofurans

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3
Q

What is the drug name for sulfonamides and trimethoprim?

A

Trimethoprim-sulfamethoxazole

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4
Q

What is the drug name for Nitrofurans?

A

nitrofurantoin

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5
Q

All metabolic processes inhibitor drugs are derive from?

A

Synthetic

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6
Q

Disrupt the folic acid pathway by binding to dihydropteroate to dyhydropteroate synthase

A

Sulfonamides

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7
Q

Disrupt the folic acid pathway by binding to dihydropteroate to Dihydrofolate reductase

A

Trimethoprim

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8
Q

Exact mechanisms uncertain but probable bacterial enzyme targets and direct DNA damage

A

Nitrofurans

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9
Q

Treatment for UTI only?

A

Nitrofurans

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