NSAIDS Flashcards
1
Q
Indomethacin
A
Class: Non-selective NSAID
Mech: Eliminate pain, reduce inflammation (but does NOT slow progression of disease)
Thera: Rheumatoid arthritis, acute gouty arthritis
Tox: Gastric and duodenal ulcers
2
Q
Naproxen (Aleve)
A
Class: Non-selective NSAID
Mech: Eliminate pain, reduce inflammation (but does NOT slow progression of disease)
Thera: Rheumatoid arthritis, acute gouty arthritis
Tox: Gastric and duodenal ulcers
3
Q
COX2 inhibitors (celecoxib)
A
Class: Selective NSAID
Mech: Eliminate pain, reduce inflammation (but does NOT slow progression of disease)
Thera: Supersede conventional NSAIDs for rheumatoid arthritis
Tox: Gastric and duodenal ulcers **50% fewer than traditional NSAIDs
