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Pharmacology > Adrenergic Receptor Antagonists > Flashcards

Adrenergic Receptor Antagonists Flashcards

1
Q

Phentolamine

A

Class: Non-selective a antagonist

Mech: Antagonist: a1, a2

Thera: Pheochromocytoma, Raynauds, frostbite

Tox: Postural hypotension, inhibit ejaculation

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2
Q

Phenoxybenzamine

A

Class: Non-selective a antagonist

Mech: Antagonist: a1, a2
Non-competitive blocker (covalent bond to receptor)

Thera: Pheochromocytoma, Raynauds, frostbite

Tox: Postural hypotension, inhibit ejaculation

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3
Q

Prazosin

A

Class: a1 selective antagonist

Mech: Antagonist: a1

Thera: Primary HTN, BPH

Tox: Postural hypotension (just with first dose)

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4
Q

Terazosin

A

Class: a1 selective antagonist

Mech: Antagonist: a1

Thera: Primary HTN, BPH

Tox: Postural hypotension (just with first dose)

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5
Q

Propanolol

A

Class: Non-selective B-antagonist (1st generation)

Mech: Antagonist: B1, B2

Thera: Angina, HTN, Arrhythmias

Tox: Bradycardia, Bronchoconstriction, sexual dysfunction

Misc: Gold standard

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6
Q

Timolol

A

Class: Non-selective B-antagonist (1st generation)

Mech: Antagonist: B1, B2

Thera: Glaucoma

Tox: Bradycardia, Bronchoconstriction, sexual dysfunction

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7
Q

Metoprolol

A

Class: B1 selective antagonist (2nd generation)

Mech: Antagonist B1

Thera: HTN, angina, arrhythmias, CHF

Tox: Bradycardia, Sexual dysfunction

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8
Q

Atenolol

A

Class: B1 selective antagonist (2nd generation)

Mech: Antagonist B1

Thera: HTN, angina, arrhythmias, CHF

Tox: Bradycardia, Sexual dysfunction

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9
Q

Bisoprolol

A

Class: B1 selective antagonist (2nd generation)

Mech: Antagonist B1

Thera: HTN, angina, arrhythmias, CHF

Tox: Bradycardia, Sexual dysfunction

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10
Q

Carvedilol

A

Class: Non-selective B-antagonist (3rd generation “A”)

Mech: Antagonist: B1, B2

Thera: CHF, HTN

Tox: Bradycardia, fatigue

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11
Q

Labetalol

A

Class: Non-selective B-antagonist (3rd generation “A”)

Mech: Antagonist: B1, B2

Thera: CHF, HTN

Tox: Bradycardia, fatigue

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12
Q

Betaxolol

A

Class: B1 selective antagonist (3rd generation “B”)

Mech: Antagonist: B1

Thera: CHF, HTN

Tox: Bradycardia

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Pharmacology (33 decks)

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