Miscellaneous Histamine/Serotonin Class Drugs

Question 1

Cyproheptadine

Answer 1

Class: N/A

Mech: Antihistaminic and antiserotonergic

Thera: Skin allegies (urticaria, anti5HT1), diarrhea of carcinoid syndrome (anti-5HT2)

Tox: Sedation, antimuscarine

Question 2

Ketanserin

Answer 2

Class: N/A

Mech: Selective 5 HT2A, 2C receptor antagonist as well as a1 and H1 antagonist

Thera: Antihypertensive (relaxes vascular and tracheal smooth muscle), antiplatelet aggregation.

Question 3

Odansetron

Answer 3

Class: N/A

Mech: 5HT3 receptor antagonists

Thera: N-V in chemo

Question 4

Triptans

Answer 4

Class: Non-ergot serotonin analogs

Mech: 5HT1B, D receptor agonist

Thera: Effective 70% migraine treatment

Tox: N/A