Normal labour and puerperium Flashcards
Define labour
Physiological process during which the fetus, membranes, umbilical cord and placenta are expelled from the uterus
What may initiate labour
- change in oestrogen/progesterone ratio
- fetal adrenals and pituitary hormones
- myometrial stretch increasing excitability
- mechanical stretch of cervix and stripping of fetal membranes
- fergusons reflex
What is the role of progesterone in influencing onset of labour?
Keeps the uterus settled
Prevents the formation of gap junctions
Hinders the ocntractibility of myocytes
What is the role of oestrogen in the onset of labour?
Makes the uterus contract
Promotes prostaglandin production
What is the role of oxytocin in the onset of labour?
Initiates and sustains contractions
Acts on decidual tissue to promote prostaglandin release
Where is oxytocin synthesised?
In decidual and extraembryonic fetal tissue in the placenta
What happens to the number of oxytocin receptors near the end of pregnancy?
Number of receptors increases in myometrial and decidual tissues near the end of pregnancy
What is the role of pulmonary surfactant secreted into amniotic fluid
Stimulates prostaglandin synthesis
What does increase in production of fetal cortisol stimulate?
An increase in maternal estriol
What does increase in myometrial oxytocin receptors cause?
Phosphatase C activity and subsequent increase in cytosolitic calcium and uterine contractility
What is the role of liquor?
Nurtures and protects fetus and facilitates movement
What is the timing of rupture of membranes?
- pre-term
- pre-labour
- first stage
- second stage
- born in a caul
What does cervical tissue consist of?
Collagen tissue mainly (types 1, 2, 3, 4) smooth muscle, elastin, held together by connective tissue ground substance
Describe the processes in cervical softening?
- increase in hyaluronic acid gives increase in molecules among collagen fibres
- decrease in bridging among collagen fibres gives decrease in firmness of cervix
What happens in cervical ripening?
- decrease in collagen fibre alignment
- decrease in collagen fibre strength
- decrease in tensile strength of the cervical matrix
- increase in cervical decorin (dermatan sulphate proteoglycan 2)
What is the bishops score?
- position
- consistency
- effacement
- dilatation
- station in pelvis
most simple way to determine if it is safe to induce labour
What are the stages of labour?
- first stage
- latent phase up to 3-4cms dilatation
- active stage 4cms-10cms (full dilatation)
- second stage
- full dilatation- delivery of baby
- third stage
- delivery of baby- expulsion of placenta and membranes
What happens in the latent phase of 1st stage of labour?
- mild irregular contractions
- cervix shortens and softens, duration variable
may last an uncomfortable few days…
What happens in the active phase of labour?
- 4cms -> full dilatation
- slow descent of the presenting part
- contractions progressively become more rhythmic and stronger
- normal progress is assessed at 1-2cms per hour
- analgesia, mobility and parity is increased variably
What is the second stage of labour?
Complete dilatation of the cervix (10cm) to delivery of the baby
When is the second stage of labour considered to be prolonged?
- in nulliparous women- if it exceeds 3 hours if there is regional anaesthesia, or 2 hours without
- in multiparous women, the second stage considered prolonged if it exceeds 2 hours with regional analgesia or 1 hour without
What is the third stage of labour?
Delivery of the baby to expulsion of the placenta and foetal membranes
Average duration 10 minutes but can be 3 minutes or longer
When is preparation made for removal of the placenta and fetal membranes under GA?
after 1 hour
Describe expectant and active management of the third stage of labour?
Expectant: spontaenous delivery of the placenta
Active management: use of oxytoxic drugs and controlled cord traction is preferred for lowering risk of post partum haemorrhage
What are braxton-hicks contractions?
Tightening of the uterine muscles, thought to be to aid the body prepare for birth
Can start 6 weeks into pregnancy but more usually felt in the third trimester
What is the character of braxton hicks contractions?
Irregular, do not increase in frequency or intensity
Resolve with ambulation or change in activity
Relatively painless
When do true labour contractions happen?
Under the influence of the release of oxytocin, which stimulates the uterus to contract
What is true labour?
When the timing of contractions become evenly spaced, and the time between them gets shorter and shorter.
Length of contraction lasts increases 10s-45s
WIll get more intense and painful over time
What are the three key factors in labour?
Power: uterine contraction
Passage: maternal pelvis
Passenger: Foetus
What contributes to the power of contractions?
Uterine muscle: Smooth muscle (myocyte) in connective tissue (collagen and elastin) density highest at the fundus
Pacemaker: region of the tubal ostia, wave spreads in a downward direction
Synchronisation of contractions waves from both ostia
Polarity: upper segment contracts and relaxes, lower segment and cervix stretch, dilate and relax
Normal contractions have a fundal dominance with a regular paterrern and an adequate resting tone