Histology of the Breast Flashcards
What kind of gland is the breast?
Subcutaenous
Describe the overall structure of the breast
- made up of 15-25 lobes, each consisting of a compound tubulo-acinar gland, drains via a serious of ducts leading to the nipple
- dense fibrous tissue adjacent to the lobules, surrounded by adipose tissue
What are suspensory ligaments?
some larger condensations that extend from the dermis of the skin to the deep fascia overlying the muscle of the anterior chest wall
What is the basic functional unit of the breast?
Terminal duct lobular unit
What do terminal ductules lead to?
Lead into an intralobular collecting duct which leads into the lactiferous duct for that lobe
What do lactiferous ducts lead to?
Nipple, passing through an expanded duct region near the nipple termed the lactiferous sinus
What is present inside a mamary gland
Atery and vein pain
Secretory Lobules
Fibrocollagenous tissue
Adipose tissue
Ducts
The lobule exhibits both _______ and _______ ducts, rudimentary secretory _____ and is surrounded by dense _______ ________ tissue.
Looser connective tissue surrounds the ______ within the lobule (allowing for rapid _________ during _______)
There is _______ tissue present between lobules
The lobule exhibits both extralobular and intralobular ducts, rudimentary secretory acini and is surrounded by dense fibrocollagenous connective tissue.
Looser connective tissue surrounds the acini within the lobule (allowing for rapid expansion during pregnancy)
There is adipose tissue present between lobules
Within the lobule the secretory ________ cells line the acini and vary from ______ to _______
Within the lobule the secretory epithelial cells line the acini and vary from cuboidal to columnar
The secretory cells of the acinus are surrounded by ________ cells (MEp) which appear ____. These are ________ epithelial cells which are in turn surrounded by the _____ _______.
The secretory cells of the acinus are surrounded by myoepithelial cells (MEp) which appear pink. These are contractile epithelial cells which are in turn surrounded by the basal lamina.
What lines larger ducts such as the lactiferous duct?
Lined by epithelium that varies from a thin stratified squamous to a stratified cuboidal
What may be seen in staining a lactiferous duct
Red staining of coagulated proteinaceous material
What do mammary glands resemble?
Modified sweat glands
The nipple has a wrinkled surface and is covered by a thin, highly pigmented ________ ______ ______ epithelium. It has a core of ____ ______ _______ tissue mixed with bundles of ______ muscle.
The nipple has a wrinkled surface and is covered by a thin, highly pigmented keratinized stratified squamous epithelium. It has a core of dense irregular connective tissue mixed with bundles of smooth muscle.
As the lactiferous duct approaches the surface, it becomes lined by ______ _______ epithelium, however deeper it is lined by _______ ________ epithelium.
Deeper still the duct lining may become only ___ cell thick.
Several sebaceous glands are present, and in it is clear that these end directly on the _____ __ ___ ____. The core of the nipple has __________ tissue mixed with _____ muscle bundles.
As the lactiferous duct approaches the surface, it becomes lined by stratified squamous epithelium, however deeper it is lined by stratified cuboidal epithelium.
Deeper still the duct lining may become only one cell thick.
Several sebaceous glands are present, and in it is clear that these end directly on the surface of the skin. The core of the nipple has fibrocollagenous tissue mixed with smooth muscle bundles.
