Nonprotein Nitrogen Flashcards

Exam 1

1
Q

Which nonprotein nitrogen fraction constitutes nearly half of the npn substances in the blood

A

Urea

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2
Q

Prerenal hyperuricemia is caused by

A

Congenital heart failure

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3
Q

A technologist obtain Zebulon value of 61 mg per deciliter and serum creatinine value of 3.1 mg per deciliter on a patient. These results indicate

A

Renal failure. Elevated BUN and creatinine

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4
Q

A BUN of 9 mg per deciliter is obtained by a technologist. What is the urea concentration. B UN x 2.14 = urea

A

19.3 mg/dl

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5
Q

Creatinine clearance is used to estimate the

A

Glomerular filtration rate

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6
Q

But Jeffe reaction is the basis for method involving the quantitation of

A

Creatinine

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7
Q

Creatinine is formed from the catabolism of

A

Creatine

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8
Q

In the jaffe reaction, a red orange chromogen is formed when creatinine reacts with

A

Picric acid

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9
Q

In the Jaffe method two compounds give a positive interference in kinetic creatinine measurement they are

A

Pyruvate and acetoacetate

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10
Q

Substances known to increase results when measuring creatinine by the Jaffe reaction include all of the following

A

Glucose, Alpha keto acids, ascorbate

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11
Q

What represents the end product of purine metabolism in humans

A

Uric acid

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12
Q

A patient with glomerulonephritis would present the following serum results

A

Increased bun

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13
Q

A person cannot have a low creatinine clearance and a normal serum creatinine level

A

True

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14
Q

Ammonia is coupled with what molecule in the liver to create urea

A

CO2

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15
Q

Increase in the plasma concentration of urea

A

Azotemia

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16
Q

Increase in urea due to pathophysiologic processes that are not directly related to the kidney

A

Prerenal azotemia

17
Q

Increased in urea caused by lesions in the kidney

A

Renal azotemia

18
Q

Increase in urea in the blood are secondary to pathophysiologic processes that also affect the glomerular filtration rate but are not directly related to lesions in the kidney

A

Post renal azotemia

19
Q

Clinical syndrome occurring with prolonged azotemia

20
Q

Monosodium urate crystals will produce what color polarization on X & Y axis

A

Yellow on x axis and blue on y axis

21
Q

What is associated with elevated plasma uric acid concentrations

A

Gout, renal disease, leach nyhand syndrome

22
Q

Increased hydrostatic pressure, decrease oncotic pressure

A

Transudate

23
Q

Increased capillary permeability, decrease lymphatic absorption

24
Q

Low protein, low enzyme content, low cholesterol ratio, low LD ratio, less than 50% total protein, clear, pale yellow

A

Transudate

25
Cloudy, variable color, increased bilirubin, glucose is less than or equal to serum level, total proteins above 50%, LD ratios elevated, cholesterol is increased, hi enzyme content, high protein more than 4%
Exudate
26
A technologist obtains a urea N value of 61 and serum creatinine value of 2.5 which are both elevated results these results indicate
Urinary tract obstruction
27
Uric acid is the final product of
Purine metabolism
28
Ammonia concentrations are usually measured to evaluate
Hepatic encephalopathy
29
When calculating creatinine clearance using the mdrd equation, which of the following factors are considered
Body mass
30
Serum creatinine levels may be falsely elevated when a patient is taking cephalosporin
True
31
When measuring ammonia blood levels, which of the following might cause a false increase in the analyte
The patient had two cigarettes 15 minutes prior to blood draw
32
A complete deficiency of hypoxanthine guanine phosphoribosyltransferase results in which disease
Lesch Nyhan syndrome