Nonprotein Nitrogen Flashcards
Exam 1
Which nonprotein nitrogen fraction constitutes nearly half of the npn substances in the blood
Urea
Prerenal hyperuricemia is caused by
Congenital heart failure
A technologist obtain Zebulon value of 61 mg per deciliter and serum creatinine value of 3.1 mg per deciliter on a patient. These results indicate
Renal failure. Elevated BUN and creatinine
A BUN of 9 mg per deciliter is obtained by a technologist. What is the urea concentration. B UN x 2.14 = urea
19.3 mg/dl
Creatinine clearance is used to estimate the
Glomerular filtration rate
But Jeffe reaction is the basis for method involving the quantitation of
Creatinine
Creatinine is formed from the catabolism of
Creatine
In the jaffe reaction, a red orange chromogen is formed when creatinine reacts with
Picric acid
In the Jaffe method two compounds give a positive interference in kinetic creatinine measurement they are
Pyruvate and acetoacetate
Substances known to increase results when measuring creatinine by the Jaffe reaction include all of the following
Glucose, Alpha keto acids, ascorbate
What represents the end product of purine metabolism in humans
Uric acid
A patient with glomerulonephritis would present the following serum results
Increased bun
A person cannot have a low creatinine clearance and a normal serum creatinine level
True
Ammonia is coupled with what molecule in the liver to create urea
CO2
Increase in the plasma concentration of urea
Azotemia
Increase in urea due to pathophysiologic processes that are not directly related to the kidney
Prerenal azotemia
Increased in urea caused by lesions in the kidney
Renal azotemia
Increase in urea in the blood are secondary to pathophysiologic processes that also affect the glomerular filtration rate but are not directly related to lesions in the kidney
Post renal azotemia
Clinical syndrome occurring with prolonged azotemia
Uremia
Monosodium urate crystals will produce what color polarization on X & Y axis
Yellow on x axis and blue on y axis
What is associated with elevated plasma uric acid concentrations
Gout, renal disease, leach nyhand syndrome
Increased hydrostatic pressure, decrease oncotic pressure
Transudate
Increased capillary permeability, decrease lymphatic absorption
Exudate
Low protein, low enzyme content, low cholesterol ratio, low LD ratio, less than 50% total protein, clear, pale yellow
Transudate