Nonprotein Nitrogen Flashcards

Exam 1

1
Q

Which nonprotein nitrogen fraction constitutes nearly half of the npn substances in the blood

A

Urea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Prerenal hyperuricemia is caused by

A

Congenital heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

A technologist obtain Zebulon value of 61 mg per deciliter and serum creatinine value of 3.1 mg per deciliter on a patient. These results indicate

A

Renal failure. Elevated BUN and creatinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A BUN of 9 mg per deciliter is obtained by a technologist. What is the urea concentration. B UN x 2.14 = urea

A

19.3 mg/dl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Creatinine clearance is used to estimate the

A

Glomerular filtration rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

But Jeffe reaction is the basis for method involving the quantitation of

A

Creatinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Creatinine is formed from the catabolism of

A

Creatine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In the jaffe reaction, a red orange chromogen is formed when creatinine reacts with

A

Picric acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In the Jaffe method two compounds give a positive interference in kinetic creatinine measurement they are

A

Pyruvate and acetoacetate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Substances known to increase results when measuring creatinine by the Jaffe reaction include all of the following

A

Glucose, Alpha keto acids, ascorbate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What represents the end product of purine metabolism in humans

A

Uric acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A patient with glomerulonephritis would present the following serum results

A

Increased bun

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A person cannot have a low creatinine clearance and a normal serum creatinine level

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ammonia is coupled with what molecule in the liver to create urea

A

CO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Increase in the plasma concentration of urea

A

Azotemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Increase in urea due to pathophysiologic processes that are not directly related to the kidney

A

Prerenal azotemia

17
Q

Increased in urea caused by lesions in the kidney

A

Renal azotemia

18
Q

Increase in urea in the blood are secondary to pathophysiologic processes that also affect the glomerular filtration rate but are not directly related to lesions in the kidney

A

Post renal azotemia

19
Q

Clinical syndrome occurring with prolonged azotemia

A

Uremia

20
Q

Monosodium urate crystals will produce what color polarization on X & Y axis

A

Yellow on x axis and blue on y axis

21
Q

What is associated with elevated plasma uric acid concentrations

A

Gout, renal disease, leach nyhand syndrome

22
Q

Increased hydrostatic pressure, decrease oncotic pressure

A

Transudate

23
Q

Increased capillary permeability, decrease lymphatic absorption

A

Exudate

24
Q

Low protein, low enzyme content, low cholesterol ratio, low LD ratio, less than 50% total protein, clear, pale yellow

A

Transudate

25
Q

Cloudy, variable color, increased bilirubin, glucose is less than or equal to serum level, total proteins above 50%, LD ratios elevated, cholesterol is increased, hi enzyme content, high protein more than 4%

A

Exudate

26
Q

A technologist obtains a urea N value of 61 and serum creatinine value of 2.5 which are both elevated results these results indicate

A

Urinary tract obstruction

27
Q

Uric acid is the final product of

A

Purine metabolism

28
Q

Ammonia concentrations are usually measured to evaluate

A

Hepatic encephalopathy

29
Q

When calculating creatinine clearance using the mdrd equation, which of the following factors are considered

A

Body mass

30
Q

Serum creatinine levels may be falsely elevated when a patient is taking cephalosporin

A

True

31
Q

When measuring ammonia blood levels, which of the following might cause a false increase in the analyte

A

The patient had two cigarettes 15 minutes prior to blood draw

32
Q

A complete deficiency of hypoxanthine guanine phosphoribosyltransferase results in which disease

A

Lesch Nyhan syndrome