Liver Function Flashcards
What type of jaundice is due to hemolysis
Prehepatic
Which type of jaundice is due to hepatocellular dysfunction caused by viruses or toxins
Hepatic
Which type of jaundice is due to bile duct obstruction
Postherpetic
What is formed in the colon by bacteria, which metabolizes bile.
Urobilinogen
What is water insoluble, a breakdown product of hemoglobin, and is in the plasma bound to albumin that is not filtered in the kidneys
Unconjugated bilirubin or indirect
What is water soluble and is excreted into the bile duct system, then into the gallbladder as bile. And can be excreted in the kidneys
Conjugated bilirubin or direct
What are the 3 liver disease enzymes
Aspartate aminotransferase, alkaline phosphatase, alanine aminotransferase
Alcohol induced the synthesis of
GGT
The best liver enzyme to evaluate liver function
ALT
The tissue that has the highest activity of both alt and AST relative to serum
Liver
The I isoenzyme ld4 and ld5 are elevated in
Liver disease
Which enzyme is most useful in establishing the hepatic origin of an elevated serum alkaline phosphatase
y-glutamyltranspeptidase
What is colorless, produced by oxidative actions of intestinal bacteria, undergoes significant enterohepatic circulation, and fecal levels decreased in biliary obstruction
Urobilinogen
Which cases of jaundice is due to a defect in the uptake of bilirubin with the hepatocyte resulting in increases in serum unconjugated bilirubin
Gilbert’s syndrome
What is the major fate of the bilirubin excreted into the intestine
Conversion to urobilinogen by the flora of the large intestine
A negative hbsag and anti HBC antibody with a positive anti HBS antibody indicates
Immunization with hepatitis B vaccine
The liver enzyme responsible for bilirubin conjugation is
Glucuronyl transferase
Urinary urobilinogen is usually increased in hepatic obstruction because of
A higher percentage of reabsorbed urobilinogen reaching the circulation
What substance gives feces its normal color
Urobilin
The most widely used methods for bilirubin measurement are those based on the
Jendrassik grof method
What liver enzyme will be increased to a markedly increased in alcoholic cirrhosis
GGT
