Liver Function Flashcards

1
Q

What type of jaundice is due to hemolysis

A

Prehepatic

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2
Q

Which type of jaundice is due to hepatocellular dysfunction caused by viruses or toxins

A

Hepatic

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3
Q

Which type of jaundice is due to bile duct obstruction

A

Postherpetic

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4
Q

What is formed in the colon by bacteria, which metabolizes bile.

A

Urobilinogen

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5
Q

What is water insoluble, a breakdown product of hemoglobin, and is in the plasma bound to albumin that is not filtered in the kidneys

A

Unconjugated bilirubin or indirect

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6
Q

What is water soluble and is excreted into the bile duct system, then into the gallbladder as bile. And can be excreted in the kidneys

A

Conjugated bilirubin or direct

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7
Q

What are the 3 liver disease enzymes

A

Aspartate aminotransferase, alkaline phosphatase, alanine aminotransferase

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8
Q

Alcohol induced the synthesis of

A

GGT

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9
Q

The best liver enzyme to evaluate liver function

A

ALT

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10
Q

The tissue that has the highest activity of both alt and AST relative to serum

A

Liver

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11
Q

The I isoenzyme ld4 and ld5 are elevated in

A

Liver disease

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12
Q

Which enzyme is most useful in establishing the hepatic origin of an elevated serum alkaline phosphatase

A

y-glutamyltranspeptidase

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13
Q

What is colorless, produced by oxidative actions of intestinal bacteria, undergoes significant enterohepatic circulation, and fecal levels decreased in biliary obstruction

A

Urobilinogen

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14
Q

Which cases of jaundice is due to a defect in the uptake of bilirubin with the hepatocyte resulting in increases in serum unconjugated bilirubin

A

Gilbert’s syndrome

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15
Q

What is the major fate of the bilirubin excreted into the intestine

A

Conversion to urobilinogen by the flora of the large intestine

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16
Q

A negative hbsag and anti HBC antibody with a positive anti HBS antibody indicates

A

Immunization with hepatitis B vaccine

17
Q

The liver enzyme responsible for bilirubin conjugation is

A

Glucuronyl transferase

18
Q

Urinary urobilinogen is usually increased in hepatic obstruction because of

A

A higher percentage of reabsorbed urobilinogen reaching the circulation

19
Q

What substance gives feces its normal color

A

Urobilin

20
Q

The most widely used methods for bilirubin measurement are those based on the

A

Jendrassik grof method

21
Q

What liver enzyme will be increased to a markedly increased in alcoholic cirrhosis

A

GGT