Liver Function Flashcards
What type of jaundice is due to hemolysis
Prehepatic
Which type of jaundice is due to hepatocellular dysfunction caused by viruses or toxins
Hepatic
Which type of jaundice is due to bile duct obstruction
Postherpetic
What is formed in the colon by bacteria, which metabolizes bile.
Urobilinogen
What is water insoluble, a breakdown product of hemoglobin, and is in the plasma bound to albumin that is not filtered in the kidneys
Unconjugated bilirubin or indirect
What is water soluble and is excreted into the bile duct system, then into the gallbladder as bile. And can be excreted in the kidneys
Conjugated bilirubin or direct
What are the 3 liver disease enzymes
Aspartate aminotransferase, alkaline phosphatase, alanine aminotransferase
Alcohol induced the synthesis of
GGT
The best liver enzyme to evaluate liver function
ALT
The tissue that has the highest activity of both alt and AST relative to serum
Liver
The I isoenzyme ld4 and ld5 are elevated in
Liver disease
Which enzyme is most useful in establishing the hepatic origin of an elevated serum alkaline phosphatase
y-glutamyltranspeptidase
What is colorless, produced by oxidative actions of intestinal bacteria, undergoes significant enterohepatic circulation, and fecal levels decreased in biliary obstruction
Urobilinogen
Which cases of jaundice is due to a defect in the uptake of bilirubin with the hepatocyte resulting in increases in serum unconjugated bilirubin
Gilbert’s syndrome
What is the major fate of the bilirubin excreted into the intestine
Conversion to urobilinogen by the flora of the large intestine