Lipids Flashcards

Exam 1

1
Q

What method for lipoprotein electrophoresis depends on charge and molecular size

A

Polyacrylamide gel

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2
Q

Chylomicrons

A

A lipoprotein produced in the intestinal mucosa, primary function is to carry dietary lipids to the liver, remains at the origin during lipoprotein electrophoresis

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3
Q

The lipoprotein that contains the greatest amount of protein is called

A

HDL

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4
Q

Several enzymatic triglyceride methods measure the production or consumption of

A

Nadh

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5
Q

The most likely cause for serum or plasma to appear milky is the presence of

A

Chylomicrons

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6
Q

In the car on Metric determination of cholesterol using the enzyme cholesterol oxidase, the agent that oxidizes the colorless organic compound 4 aminoantipyrine to a pink complex is

A

Hydrogen peroxide

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7
Q

Which lipoprotein is the major carrier of cholesterol to peripheral tissues

A

LDL

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8
Q

What is the presumed effect in most cases of familial type to a hyper lipoprotein anemia

A

Defective receptors for LDL

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9
Q

Hyperchylomicronemia type 1 is childhood has been associated with which of the following deficiencies

A

A deficiency of a Apo C II

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10
Q

HDL quantitation is used in correlating the risk of

A

Coronary heart disease

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11
Q

Triglycerides are transported in plasma mostly in the form of large triglyceride which particles called

A

Chylomicrons

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12
Q

The lipoprotein that contains the greatest amount of protein is called

A

HDL

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13
Q

Which lipoprotein is the major carrier of cholesterol to peripheral tissue

A

LDL

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14
Q

Cholesterol functions in the

A

Steroid hormone precursor, membrane structure, bile acid precursor

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15
Q

What is the major fatty acid Ester fide to cholesterol in normal serum

A

Linoleic

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16
Q

The primary function is to carry dietary exogenesis lipids to the liver, remains at the origin during lipoprotein electrophoresis, lipoprotein is produced in the intestinal mucosa

A

Chylomicrons

17
Q

Premature arterial sclerosis can occur when what is elevated

18
Q

High levels of which lipoprotein class are associated with decreased risk of arthro sclerosis

19
Q

Dietary lipids are first broken down and packaged into

A

Micelles which are then absorbed by the intestines

20
Q

What percentage of total cholesterol is typically in LDL, HDL, VLDL

A

65% LDL, 25% HDL, 10% VLDL

21
Q

A disease of the arteries that Supply blood and oxygen to the heart that causes decreased blood flow to the heart muscle

A

Coronary artery disease

22
Q

Removes excess cholesterol and takes it from tissues back to the liver where cholesterol is converted to bile salts and excreted

23
Q

Routes cholesterol through the body from liver to peripheral tissues

24
Q

Most cells especially the liver and adipose cells can synthesize triglycerides

A

Endogenous

25
Ingested in the diet saturated fats generally solid at RT, polyunsaturated fats liquid at RT
Exogenous
26
Transport endogenous triglycerides to the tissues that need triglycerides
VLDL
27
Act as the glue that holds the Apoproteins to the lipoproteins
Phospholipids
28
What are produced by the intestines and degraded in the liver
Chylomicrons
29
What is formed as a result of lipolysis of VLDL
LDL
30
What are synthesized from carbohydrate precursors and are essential fatty acids
Fatty acids
31
Fluid component of cytoplasm
Cytosol
32
What comprises 98% of fat found in food is synthesized in liver hepatocyte and transported by chylomicrons and vldl
Triglycerides
33
Inside a level in water and can be extracted from cells only by organic solvents
Lipids
34
What are the four major Pathways involved in lipoprotein metabolism
Endogenous pathway, exofenous pathway, lipid absorption, reverse cholesterol transport pathway
35
Caused by lipids in form of Esther fide cholesterol being deposited in artery walls resulting in fatty streaks
Arteriosclerosis