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Clin Chem > Lipids > Flashcards

Lipids Flashcards

Exam 1

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1
Q

What method for lipoprotein electrophoresis depends on charge and molecular size

A

Polyacrylamide gel

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2
Q

Chylomicrons

A

A lipoprotein produced in the intestinal mucosa, primary function is to carry dietary lipids to the liver, remains at the origin during lipoprotein electrophoresis

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3
Q

The lipoprotein that contains the greatest amount of protein is called

A

HDL

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4
Q

Several enzymatic triglyceride methods measure the production or consumption of

A

Nadh

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5
Q

The most likely cause for serum or plasma to appear milky is the presence of

A

Chylomicrons

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6
Q

In the car on Metric determination of cholesterol using the enzyme cholesterol oxidase, the agent that oxidizes the colorless organic compound 4 aminoantipyrine to a pink complex is

A

Hydrogen peroxide

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7
Q

Which lipoprotein is the major carrier of cholesterol to peripheral tissues

A

LDL

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8
Q

What is the presumed effect in most cases of familial type to a hyper lipoprotein anemia

A

Defective receptors for LDL

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9
Q

Hyperchylomicronemia type 1 is childhood has been associated with which of the following deficiencies

A

A deficiency of a Apo C II

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10
Q

HDL quantitation is used in correlating the risk of

A

Coronary heart disease

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11
Q

Triglycerides are transported in plasma mostly in the form of large triglyceride which particles called

A

Chylomicrons

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12
Q

The lipoprotein that contains the greatest amount of protein is called

A

HDL

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13
Q

Which lipoprotein is the major carrier of cholesterol to peripheral tissue

A

LDL

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14
Q

Cholesterol functions in the

A

Steroid hormone precursor, membrane structure, bile acid precursor

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15
Q

What is the major fatty acid Ester fide to cholesterol in normal serum

A

Linoleic

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16
Q

The primary function is to carry dietary exogenesis lipids to the liver, remains at the origin during lipoprotein electrophoresis, lipoprotein is produced in the intestinal mucosa

A

Chylomicrons

17
Q

Premature arterial sclerosis can occur when what is elevated

A

LDL

18
Q

High levels of which lipoprotein class are associated with decreased risk of arthro sclerosis

A

HDL

19
Q

Dietary lipids are first broken down and packaged into

A

Micelles which are then absorbed by the intestines

20
Q

What percentage of total cholesterol is typically in LDL, HDL, VLDL

A

65% LDL, 25% HDL, 10% VLDL

21
Q

A disease of the arteries that Supply blood and oxygen to the heart that causes decreased blood flow to the heart muscle

A

Coronary artery disease

22
Q

Removes excess cholesterol and takes it from tissues back to the liver where cholesterol is converted to bile salts and excreted

A

HDL

23
Q

Routes cholesterol through the body from liver to peripheral tissues

A

LDL

24
Q

Most cells especially the liver and adipose cells can synthesize triglycerides

A

Endogenous

25
Q

Ingested in the diet saturated fats generally solid at RT, polyunsaturated fats liquid at RT

A

Exogenous

26
Q

Transport endogenous triglycerides to the tissues that need triglycerides

A

VLDL

27
Q

Act as the glue that holds the Apoproteins to the lipoproteins

A

Phospholipids

28
Q

What are produced by the intestines and degraded in the liver

A

Chylomicrons

29
Q

What is formed as a result of lipolysis of VLDL

A

LDL

30
Q

What are synthesized from carbohydrate precursors and are essential fatty acids

A

Fatty acids

31
Q

Fluid component of cytoplasm

A

Cytosol

32
Q

What comprises 98% of fat found in food is synthesized in liver hepatocyte and transported by chylomicrons and vldl

A

Triglycerides

33
Q

Inside a level in water and can be extracted from cells only by organic solvents

A

Lipids

34
Q

What are the four major Pathways involved in lipoprotein metabolism

A

Endogenous pathway, exofenous pathway, lipid absorption, reverse cholesterol transport pathway

35
Q

Caused by lipids in form of Esther fide cholesterol being deposited in artery walls resulting in fatty streaks

A

Arteriosclerosis

Clin Chem (15 decks)

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