Nonpolar hormones: Thyroid Flashcards
What is the role of the thyroid hormone?
Increases metabolism and protein synthesis and is necessary for growth and development
Higher metabolism results in the
Rate of glucose, fat and protein
catabolism
Thyroid Hormone Disorders can be present as a hypofunctional or
hyper functional state. What are the causes of hypothyroid conditions
Hypothyroid conditions may be caused by a deficiency of iodine in the diet or a reduced secretion of thyroid hormone
What are the 2 examples of hyothyroid conditions
Cretinism seen with infants
Myxedema seen in adults
What is cretinism?
a condition of severely stunted physical and mental
growth due to untreated congenital deficiency of thyroid hormones
Thyroid hormones do what
modulate energy metabolism and
importantly influence growth and development.
Myxedema is a condition n of severe hypothyroidism seen in adults. What do changes include
Thickening of the skin
Puffy eyes
Lethargy
Mental slowness
Hypoglycemia
Hypotension
Bradycardia
Hyporthermia
Myxedema is a term used to describe the_____seen the
accumulation of a hydrophilic mucopolysaccharide in the connective
tissue.
Most commonly seen in the face.
Non-pitting edema
What is the most common cause of mxyedema and what are the treatments?
Hashimoto’s thyroiditis, thyroidectomy, medications such as lithium carbonate
Treatment-levothyroxine, (Levo-T, Synthroid, others).
What is a disease caused by hyperthyroidism?
Grave’s disease.
What is Grave’s disease
a autoimmune disease where the antibodies mimic TSH,
stimulating TH release
Symoptoms of Grave’s disease
Elevated metabolic rate
Sweating
Rapid heart rate
Weight loss
Exophthalmos (protrusion of the eyeballs) due to retraction of the
eyelids and decreased blinking
Janice noticed a lump in her neck which had been getting larger over
time. She also noticed her energy levels going down and weight gain.
What is her presumptive diagnosis? What is causing the mass in her
neck? Iodine levels are very low how could this be the cause?
Hypothyroidism. The mass is do to hypertrophy of the thyroid gland.
Iodine is necessary for the synthesis of thyroid hormone
What are two autoimmune diseases that impact the Thyroid gland?
Hashimoto’s Thyroiditis
Grave’s Disease
What are the two hypothalamic hormones that control the release of
growth hormone from the anterior pituitary?
Somatocrinin +
Somatostatin -