Addison's disease

Question 1

What is Addison’s disease caused by?

Answer 1

The autoimmune destruction of
the adrenal gland, it can be a complication of tuberculosis.

Question 2

What hormones does Addion’s disease impact?

Answer 2

Both mineral corticoid(aldosterone) and glucocorticoid (cortisol) are impacted

Question 3

Treatment consists of oral replacement therapy

Answer 3

Treatments of Addison’s disease consists

Question 4

What are the two forms of Adrenal Cortical Insufficiency?

Answer 4

-Primary or Addison’s disease which is caused by the destruction of the
adrenal gland

• Secondary which is caused by a disorder in the HPA system

Question 5

Why is ACTH elevated in Addison’s disease?

Answer 5

 The HPA feed back loop isn’t functioning do to the low levels of
Cortisol

Question 6

What is Adrenal crisis (also known as Addisonian crisis and acute adrenal insufficiency)

Answer 6

A medical emergency and potentially life-threatening situation requiring immediate emergency treatment.

Question 7

What are the risk factors of an adrenal crisis?

Answer 7

e physical stress such as infection, dehydration, trauma, or surgery, adrenal gland or pituitary
gland injury, and ending treatment with steroids such as prednisone or
hydrocortisone too earlly

Question 8

What is the role of ACTH

Answer 8

ACTH is secreted from the anterior pituitary in response to low levels
of cortisol.

Question 9

What is the hypophyseal portal?

Answer 9

A system of blood vessels/ The portal vessels deliver blood containing
regulatory factors to the capillary network
within the anterior lobe of the pituitary gland

Question 10

The superior hypophyseal artery function

Answer 10

artery delivers blood
to the capillary network in the median
eminence

Question 11

The inferior hypophyseal artery delivers

Answer 11

blood to the posterior lobs of the pituitary gland

Question 12

Hypophyseal veins carry blood containing the

Answer 12

pituitary hormones to the cardiovascular
system for delivery to the rest of the body

Question 13

The Pituitary Gland:
Releases nine important peptide hormones
 Hormones from the pituitary bind to membrane receptors and use ____

Answer 13

cAMP as second messenger

Question 14

What re the 9 hormones secreted by the the anterior pituitary gland?

Answer 14

ACTH
TSH
GH
PRL
FSH
LH
MSH
ADH
OXT

Question 15

What does ACTH stimulate?

Answer 15

Cortisol