Bruton’s Agammaglobulinemia

Question 1

an inherited immunodeficiency disease caused by mutations in the gene coding for Bruton tyrosine kinase
(BTK).

Answer 1

X-linked agammaglobulinemia (XLA), or Bruton agammaglobulinemia

Question 2

 The prognosis is good as long as patients are diagnosed and treated early with regular intravenous gamma globulin therapy
before recurrent infections appear

Answer 2

Bruton’s Agammaglobulinemia

Question 3

 Reticular dysgenesis is the most severe form of severe and is characterized bybilateral
sensorineural deafness and a lack of innate and adaptive immune
functions leading to fatal septicemia within days after birth if not
treated

Answer 3

combined
immunodeficiency (SCID

Question 4

A person is diagnosed with AIDS when

Answer 4

Normal helper T cell numbers are
about 800 to 1200 cells/mm3.

A person is usually diagnosed with AIDS when T cell count drops to 200
cells/mm3, and he or she develops certain opportunistic infections such
as pneumonia, toxoplasmosis, Kaposi’s sarcoma, and cytomegalovirus
retinitis
.

Question 5

AID malignancies include Non-Hodgkins Lymphoma and Kaposi sarcoma

Answer 5

 Non-Hodgkin Lymphoma: cancer in
lymphatic system
 Kaposi Sarcoma: cancerous tumor of
connective tissue

Question 6

a type of cancer that begins in a subset of
white blood cells called lymphocytes

Answer 6

Both Hodgkin’s lymphoma and non-Hodgkin’s lymphoma are lymphomas —what are lymphomas?.

Question 7

If in examining the cells, the presence of a specific type of abnormal cell
called a Reed-Sternberg cell is found, the lymphoma is classified
as

Answer 7

Hodgkins

Question 8

• Swollen lymph nodes in the neck, underarms or groin.
• Intermittent fevers.
• Drenching night sweats.
• Feeling tired all the time.
• Unexplained weight loss.
• Decreased appetite.
• Generalized itching.
• Abdominal pain or swelling, feeling of fullness.

Answer 8

• Hodgkin lymphoma signs may include:

Question 9

Hodgkin’s disease is considered one of the most curable forms of
cancer, especially if it is diagnosed and treated early

TRUE OR FALSE?

Answer 9

True

Question 10

• Painless, swollen lymph nodes in your neck, armpits or groin.
• Abdominal pain or swelling.
• Chest pain, coughing or trouble breathing.
• Persistent fatigue.
• Fever.
• Night sweats.
• Unexplained weight lossNon-Hodgkin’s Lymphoma
  :

Answer 10

•  Signs and symptoms of non-Hodgkin’s lymphoma may include: