NM III - Disorders of the spinal cord & Motor neurons

Question 1

motor neuron disease w/ both UMN & LMN

Answer 1

ALS = amyotrophic lateral sclerosis

Question 2

survival motor neuron 1 (SMN 1) gene

Answer 2

Spinal muscular dystrophy

Question 3

motor neuron diseases w/ only LMN

Answer 3

progressive muscular atrophy
spinal muscular atrophy,
benign focal amyotrophy

Question 4

subacute combined degeneration of the spinal cord

Answer 4

vitamin B12 deficienccy

Question 5

postgastric bypass neurologic syndrome

Answer 5

copper deficiency

Question 6

anterior 2/3 of the spinal cord

Answer 6

anterior spinal artery

Question 7

posterior 1/3 of the spinal cord

Answer 7

posterior spinal arteries

Question 8

devic’s disease, aquaporin-4

Answer 8

neuroomyelitis optica

Question 9

nitrous oxide toxicity, associated w/ B12 delpetiton

Answer 9

anesthesia paresthetica

Question 10

HIV related myelopathy

Answer 10

vacuolar myelopathy

Question 11

large radicular artery supplying lower thoracic and upper lumbar region

Answer 11

adamkiewicz

Question 12

ipsilateral loss oof motor fxn and sensation to vibration and proprioception below the level of the lesion, with contralateral loss of sensation of pain and temperature

Answer 12

brown-sequard syndrome

Question 13

syphillis

Answer 13

tabes dorsalis

Question 14

adrenomyeloneuropathy, X-linked

Answer 14

ABCD1 gene on chromosome Xq28

Question 15

chronic steroid use

Answer 15

epidural lipomatosis