Infectious Diseases of the Nervous System

Question 1

erythema chronicum migrans

Answer 1

lyme disease

Question 2

b/l facial nerve palsies

Answer 2

lyme disease (consider MS or sarcoidosis)

Question 3

meningitis, positive india ink and budding yeast

Answer 3

cryptococcus

Question 4

AIDS & MRI w/ ring enhancing masses with edema

Answer 4

toxoplasmosis & CNS lymphoma

Question 5

AIDS w/ mass lesion and positive EBV PCR

Answer 5

primary CNS lymphoma

Question 6

AIDS w/ multiple non enhancing lesions in the parieto-occipital regions. pathology showing myelin loss, giant astrocytes, and altered oligodendrocytes with enlarged nuclei and viral inclusions. “spaghetti and meatballs” on electron microscopy

Answer 6

JC virus, PML

Question 7

meningitis in the very young or very elderly

Answer 7

listeria monocytogenes

Question 8

hypo-pigmented lesions and enlarged peripheral nerves

Answer 8

mycobacterium leprae

Question 9

oculomasticatory myorrhythmia

Answer 9

whipple’s disease

Question 10

progressive dementia, 14-3-3 protien, EEG w/ periodic pattern, MRI w/ hyperintensity in the corte, bilateral thalami, pulvinar and head of the caudate

Answer 10

CJD

Question 11

encephalitis and bilateral temporal hemorrhages

Answer 11

HSV encephalitis

Question 12

nasal and mxillary necrotizing lesion and diabteic ketoacidosis

Answer 12

mucormycosis

Question 13

LMN syndrome in summer with characteristics of infectious process

Answer 13

West Nile Virus

Question 14

basal menintitis

Answer 14

Tubercolosis

Question 15

tabes dorsalis, argyll-robertson pupils

Answer 15

syphilis

Question 16

septate hyphae with acute angle branches

Answer 16

aspergillosis

Question 17

pt from underdeveloped country with seizures and cystic and calcified parenchymal lesions

Answer 17

neurocysticercosis

Question 18

negri bodies

Answer 18

rabies