New Antimicrobial deck

Question 1

What are the classes of Beta Lactams?

Answer 1

Penicillins, Antistaphlococcal, aminopenicillins, and antipseudomonal,

Question 2

What is Beta lactams mechanism of action

Answer 2

1. inhibits transpeptidase
2. activates cell destruction to break down the cell wall

Question 3

What is generation 1 penicillins?

Answer 3

Penicillin G and Penicillin V

Question 4

What is the drug of choice for treponium pallidum?

Answer 4

Penicillin G

Question 5

What is generation 1 penicillins effective against?

Answer 5

gram positive bacteria, and some small gram negative bacteria (neisseria gonorrhea)

Question 6

What is susceptible to bacterial lactamase?

Answer 6

generation 1 penicillins and aminopenicillins

Question 7

What are antistaphlococcals?

Answer 7

methicillin and dicloxacillin

Question 8

what does antistaphlococcal treat?

Answer 8

Gram positive: blepharitis and internal hordeolum

NO gram negative activity

Question 9

what drug(s) stimilate(s) wafarin metabolism?

Answer 9

methicillin and dicloxacillin

Question 10

What is beta lactamase resistant?

Answer 10

Antistaphlococcal penicillins

Question 11

What is aminopenicillins effective against?

Answer 11

mostly gram positive but some gram negative rods

Question 12

What are specific aminopenicillins

Answer 12

ampicillin, aminopenicillins, augmentin

Question 13

What is the drug of choice for listeria monocytogenes?

Answer 13

Ampicillin

Question 14

What does ampicillin treat?

Answer 14

listeria
respiratory and GIT infections

Question 15

What does amoxicillin treat?

Answer 15

has more gram negative coverage

respiratory infections
H pylori ulcers
preseptal cellulitis
darcrocystitis
pediatric hemophilus

Question 16

what does augmentin treat

Answer 16

preseptal cellulitis
internal hordeolum
darcryocystitis
hemophilus

Question 17

what is the most commonly prescribed antibiotic

Answer 17

amoxicillin

Question 18

What is the order of gram positive effective cephalosporins

Answer 18

1>2>3

Question 19

What is the order of gram negative effective cephalosporins

Answer 19

3>2>1

Question 20

what are specific first generation cephalosporins

Answer 20

cefazolin
cephalexin

Question 21

what are specific second generation cephalosporin

Answer 21

cefuroxime
cefoxitin

Question 22

what does first generation cephalosporins treat

Answer 22

gram postive: staph and strep

soft tissue infections
hordeolum
lid trauma
darcyoadenitis
dacryocystitis
respiratory and urinary tract infections

Question 23

What does second generation cephalosporin’s treat

Answer 23

more gram negative bacteria

often used in ear, skin, respiratory infections

Question 24

what more specific bacteria does second generation cephalosporin’s treat

Answer 24

hemophilus
Enterococcus
neisseria
preoteus
e. coli
klebsiella

Question 25

what more specific bacteria does third generation cephalosporin's treat

Answer 25

H pylori Enterococcus neiseccera pseudomonas e. coli klebsiella

Question 26

what are specific third generation cephalosporins

Answer 26

ceftriaxone cefixime ceftazidime

Question 27

what does third generation cepharlosporin's treat

Answer 27

gram negative bacteria orbital cellulitis (nafcillin and cephalosporin) -->IV neisseriagonorrhea

Question 28

What are specific carbapenems?

Answer 28

imipenem

Question 29

what drug causes seizures

Answer 29

imipenem's

Question 30

What is the number one drug that causes allergic reactions?

Answer 30

penicillins

Question 31

what can cause cross reactions with penicillins

Answer 31

cephalosporins with the highest being first generation

Question 32

What drugs can penetrate CSF?

Answer 32

imipenem and aztreonam

Question 33

What is the specific monobactam

Answer 33

aztreonam

Question 34

what is aztreonam effective agaisnt?

Answer 34

gram negative only aeruginosa and enterobacter

Question 35

what are the types of glycoproteins

Answer 35

vancomycin and bacitracin

Question 36

what is vancomycin's mechanism of action

Answer 36

binds to pentopeptide preventing the binding of transpeptidase

Question 37

What is the drug of choice for c diff?

Answer 37

vancomycin

Question 38

what is the drug of choice for MRSA

Answer 38

vancomycin

Question 39

what is the side effects of vancomycin

Answer 39

ototoxicity nephrotoxicity redman syndrome

Question 40

What is bacitracin's mechanism of action

Answer 40

prevents the recycling of the lipid carrier

Question 41

what is bacitracin effective against

Answer 41

gram positive

Question 42

what is bacitracin used to treat

Answer 42

blepharitis neisseria and haemophilus

Question 43

what is a side effect of bacitracin

Answer 43

nephrotoxicity

Question 44

what is polymixin's mechanism of action

Answer 44

binds to bacterial membrane phospholipids --> osmotic stress and cell death

Question 45

what is polymixin effective agaisnt

Answer 45

gram negative bacteria

Question 46

what is a side effect of polymixin B

Answer 46

nephrotoxiciy

Question 47

what antimicrobials have side effects of nephrotoxicity

Answer 47

vancomycin bacitracin polymixin B