Endocrine Pharm therapeutic uses Flashcards
Leuprolide (lupron)
suppression of estrogens and testosterone:
endometriosis and uterine fibroids, breast cancer, prostate cancer, central precocious puperty, uterine bleeding stimulation
infertility
Cetrorelix (cetrotide)
in vitro fertilization
endometriosis and uterine fibroids
prostate cancer
octreotide (sandostain)
acromegaly
Somatropin (humatrope)
GH deficiency in children and adults
Pegvisomant (somavert)
acromegally and gigantism
menotropin (repronex)
fertility issues
bromocriptine (repronex)
prolactin secreting adenomas
parkinson’s
restless leg syndrome
demopressin (DDVAP)
diabetes insipidus
conivptan (vaprisol)
hypoatremia
levothyroxine (synthroid)
hypothyroidism
propylthiouracil (PTU)
hyperthyroidism
graves disease
methimazole (tapazole)
hyperthyroidism
graves disease
ethinyl estradiol (estinyl)
Hormone Replacement Therapy
Oral birth control (combo with progestins)
micronized progesterone (prometrium)
HRT
birth control either in combo with estrogen or alone (minipill)
nogestimate (ortho)
prevents pregnancy
norethidrone (orthonovum)
prevents pregnancy
Medroxyprogesterone (depo-provera)
prevents pregnancy
minipill
prevents pregnancy
Leconorgestrol (plan B)
prevents pregnancy after unprotected sex)
mifepristone (RU 486)
aborts fetus
Group of inhibitors of steroidogenesis
cushings
adrenocortical carcinoma
prostrate cancer
pattern hair loss
estrogen receptor positive breat cancer
Tamoxifen (nolvadex D)
breast cancer
reduce risk of incidence of breast cancer in high risk women, prevents gynecomastia in body builders
testosterone gel (androgel)
1:1
HRT
delayed puberty
inoperable breast cancer in females
Testosterone 1:2 (performancing enhancing drugs
orphan status: severe burns, senile osteoporosis
abuse because increases lean body mass, muscle strength and agressiveness
Vitamin D
rickets
osteoporosis
psoriasis
DED
Teriparatide (forteo)
osteoporosis
Estrogens
osteoporosis
Alendronate (fosamax)
osteoporosis
Cortisol and hydrocortisone
HRT for addison’s disease
Prenisolone (pred forte, pred mild)
anti-inflammatory
triamcinolone (kenalog)
anti-inflammatory
methyprenisolone (medrol dosepak)
antiinflammatory
dexamethasone (decadron)
anti inflammatory
inhibitors of steroidogenesis
cushing’s syndrom
adrenocortical carcinoma
prostate cancer
pattern hair loss
estrogen receptor positive breast cancer
insulin (humulin)
DM 1 and 2
pramlintide (symlin)
DM 1 and 2
Tolbutamine (orinase)
DM 2
Repaglinide (prandin)
DM 2
Metformin (glucophage)
DM 2
Pioglitazone (actos)
DM 2
Alpha-glucoside inhibitors
DM 2 adjunct therapy
Exenatide (byetta)
DM 2 adjunct therapy
Sitagliptin (januvia)
DM 2 adjunct therapyC
Canagliflozin (inovokana)
primary therapy for DM 2 with diet and exercise