Neuroplasticity Flashcards

1
Q

what is neuroplasticity?

A

The brain’s ability to modify, change, and adapt both structure and function throughout life and in response to experience

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2
Q

what is synaptic plasticity?

A

The connection between neurons can be modified

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3
Q

what are the different processes of neuroplasticity?

A

Neurogenesis
synaptogenesis
synaptic plasticity
cortical reorganization

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4
Q

when does neuroplasticity take place?

A

constantly throughout the lifespan

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5
Q

is neuroplasticity always good?

A

no, it can be maladaptive in some cases

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6
Q

what is an example of maladaptive neuroplasticity?

A

a smoke alarm leading to a dog being scared then translates to that dog being scared of any loud sounds

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7
Q

what is homosynaptic plasticity?

A

Changes in synaptic strength localized to
a post-synaptic target neuron stimulated by its own pre-synaptic neuron

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8
Q

what is heterosynaptic plasticity?

A

activity of a neuron leads to changes in the strength of synaptic connections of other neurons

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9
Q

what are the 2 main types of short term plasticity?

A

short term potentiation
short term depression

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10
Q

what is short term potentiation?

A

short term increase in synaptic strength due to an increase in NT release

“neurons that fire together, wire together”

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11
Q

what is short term depression?

A

short term decrease in synaptic strength due to decreased availability of NT

“neurons that fire out of synch, lose their link”

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12
Q

what is long term potentiation?

A

long term increase in synaptic connections

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13
Q

what is long term depression?

A

long term decrease in synaptic connections

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14
Q

are short term changes in synaptic strength temporary or permanent changes?

A

Temporary functional changes

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15
Q

are long term changes in synaptic strength temporary or permanent changes?

A

More permanent, structural changes

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16
Q

describe the biochemical events of long term potentiation

A

Ca2+ enters the post synaptic cell as a secondary messenger

glutamate is released from the pre synaptic neuron and binds to AMPA receptors

more AMPA receptors are added to the postsynaptic membrane

increase in size, number, and length of dendritic spines

results in strengthening of synaptic transmission (LTP)

17
Q

what is required to change synaptic plasticity on a long term basis?

A
  1. Gene transcription
  2. Protein synthesis
18
Q

what is synaptic pruning?

A

a mechanism to selectively weaken synapses

19
Q
A