Neuromuscular Conditions Flashcards

1
Q

What is cerebral palsy?

A

A permanent and non-progressive motor disorder due to brain damage before birth or during the first 2 years of life.

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2
Q

What are the causes of cerebral palsy?

A
Placental insufficiency
Toxaemia
Smoking, alcohol, drugs
Infection such as toxoplasmosis, rubella, CMV and herpes type II (TORCH)
Prematurity (most common)
Anoxic injuries
Head trauma
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3
Q

What are dynamic contractures?

A

Increased muscle tone and hyperreflexia
No fixed deformity of joints
Deformity can be overcome

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4
Q

What are fixed muscle contractures?

A

Persistent spasticity and contracture
Shortened muscle tendon units
Deformity cannot be overcome

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5
Q

What are some general features of cerebral palsy?

A
Spasticity
Lack of voluntary control
Weakness
Poor co-ordination
Sensory impairment
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6
Q

What are some of the complications which can arise from cerebral palsy?

A
Motor 
Sensory (speech and hearing difficulties, visual defects)
Cognitive problems (50%)
Epilepsy
Feeding difficulties, 
Behavioural problems
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7
Q

What investigations can be done when diagnosing cerebral palsy?

A

Gait analysis
Xrays
MRI

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8
Q

What are the prerequisites of normal gait?

A
Stability in stance
Clearance in swing
Preposition of foot
Adequate step length
Energy conservation
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9
Q

What should be included in the clinical assessment of hips?

A
Sitting, lying and  prone if possible
Hip ROM - pain
Hamstring tightness
Pelvic obliquity
Spine in coronal and sagittal planes
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10
Q

What are the different levels of GMFCS hip assessment?

A

LEVEL I - Walks without Limitations
LEVEL II - Walks with Limitations
LEVEL III - Walks Using a Hand-Held Mobility Device
LEVEL IV - Self-Mobility with Limitations; May Use Powered Mobility
LEVEL V - Transported in a Manual Wheelchair

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11
Q

What medications can be used to manage spasticity?

A

Baclofen
Diazepam
Botulinum toxin
Surgery

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12
Q

What management options are available for hip deformity?

A
Soft tissue release (adductors, hamstrings) 
Bony realignment (Varus Derotation Osteotomy, Pelvic Osteotomy)
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13
Q

What is spina bifida?

A

Failure to close neural tube

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14
Q

What is the spectrum of spina bifida?

A
Occulta – benign
Meningocele
Myelomeningocele
Encephalocele
Anencephaly
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15
Q

What are the complications of myelomeningocele?

A
Hydrocephaly
Chiari II malform
Tethered cord
Urinary tract problems
Locomotor limitation
Latex allergy (3/4)
Learning disability  (1/5)
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16
Q

What investigations should be used when diagnosing muscular dystrophy?

A

Muscle biopsy
DNA
Blood enzymes
EMG