Neurology for Neurosurgeons Flashcards
Regarding types of migraine, which of the following is a migraine with neurologic symptoms (nausea, vomiting, visual aura) without headache?
● A. Classic migraine
● B. Common migraine
● C. Hemiplegic migraine
● D. Migraine equivalent
● E. Histaminic migraine
D. Migraine equivalent
For idiopathic paralysis agitans (IPA), what is the hallmark histological feature?
● A. Lewy bodies
● B. Psammoma bodies
● C. Ki67 index
● D. Stellate microglia
● E. Bence Jones proteins
A. Lewy bodies
Which of the following is classic idiopathic paralysis agitans IPA plus amyotrophic lateral sclerosis (ALS)?
● A. Parkinson-dementia complex of Guam
● B. Riley-Day
● C. Huntington’s disease (HD)
● D. Shy-Drager syndrome
● E. Olivopontocerebellar degeneration (OPC)
A. Parkinson-dementia complex of Guam
Multiple sclerosis is an idiopathic demyelinating disease of the central nervous system producing exacerbating and remitting symptoms that are disseminated in space and time. The McDonald criteria are utilized for the diagnosis. What is the
most common finding in CSF analysis?
● A. Raised opening pressure
● B. WBC count > 1000
● C. Proteins > 150
● D. Oligoclonal bands
● E. Mib-I
D. Oligoclonal bands
Amyotrophic lateral sclerosis is degeneration of anterior horn cells and corticospinal tracts in the cervical spine and medulla. The definitive treatment includes which of the following?
● A. Surgery
● B. Radiotherapy
● C. Antiviral
● D. Antibiotics
● E. None
E. None
Regarding the diagnosis of Guillain-Barre syndrome, which of the following is a universal feature?
● A. Sensory deficit
● B. Areflexia
● C. CSF pleocytosis
● D. Periventricular calcifications
● E. Unilateral facial nerve palsy
B. Areflexia
Treatment of Guillain-Barre syndrome includes which of the following?
● A. Steroids
● B. Immunoglobulins
● C. Antivirals
● D. Serial LP drainage
● E. Frontal lobectomy
B. Immunoglobulins
For treatment of acute transverse myelitis, which of the following has no role?
● A. Steroids
● B. Plasma exchange
● C. Cyclophosphamide
● D. Surgery
● E. Radiotherapy
E. Radiotherapy
Which of the following is the most common neurologic manifestation of neurosarcoidosis?
● A. Diabetes insipidus
● B. Intracranial hypotension
● C. Foix-Alajouanine syndrome
● D. Radiculopathy
● E. Sudden-onset blindness
A. Diabetes insipidus
Regarding treatment of neurosarcoidosis, which of the following has no role?
● A. Steroids
● B. Surgery
● C. Radiotherapy
● D. Methotrexate
● E. Antivirals
E. Antivirals
A patient presents in OPD with history of headache with nausea, vomiting, and photophobia. The patient also complains of pungent smell before start of headache. Along with headache the patient also has occasional neurologic deficit that resolves spontaneously within 24 hours. What kind of headache this patient has?
● A. Common migraine
● B. Classic migraine
● C. Complicated migraine
● D. Migraine equivalent
● E. Cluster headache
B. Classic migraine
Patients with parkinsonism can be treated with surgery. Previously stereotactic thalamotomy used to be done for parkinsonism which relieves tremor more than bradykinesia. Which nucleus of thalamus is targeted during this procedure?
● A. Anterolateral
● B. Posterolateral
● C. Ventrolateral
● D. Medial geniculate nucleus
● E. Lateral geniculate nucleus
C. Ventrolateral
Multiple sclerosis is an idiopathic demyelinating disease of the CNS, disseminated in time and space, with classic clinical findings of optic neuritis, paresthesias, and bladder symptoms.
Which of the following is the most common pattern of multiple sclerosis at onset?
● A. Relapsing remitting
● B. Secondary progressive
● C. Primary progressive
● D. Progressive relapsing
● E. None of the above
A. Relapsing remitting
A patient presents in OPD with slowly progressive weakness and atrophy in hands. With time the patient developed spasticity in lower extremities. The patient also developed dysarthria
and dysphagia along with tongue atrophy. EMG showed fibrillation potentials in tongue and slightly elevated protein in CSF.
What is the most likely diagnosis in this patient?
● A. Cervical spondylotic myelopathy
● B. Motor neuron disease
● C. Amyotrophic lateral sclerosis
● D. Primary lateral sclerosis
● E. Progressive muscular and spinal atrophy
C. Amyotrophic lateral sclerosis
A patient presents in emergency with weakness in lower extremities that is symmetrical in both limbs and occurred some days after sore throat. The patient gives history of slight weakness in upper limbs as well with no sensory symptoms in
upper or lower limbs. CSF examination shows elevated protein.
What is the most likely diagnosis in this patient?
● A. Motor neuron disease
● B. Myasthenia gravis
● C. Guillain-Barre syndrome
● D. Myelitis
● E. Parkinson disease
C. Guillain-Barre syndrome