Hematology Flashcards
What is the circulating blood volume (cc/kg) in adults?
● A. 1
● B. 25
● C. 50
● D. 75
● E. 100
D. 75
Platelets may be store for up to how long?
● A. 5 days
● B. 10 days
● C. 2 weeks
● D. 3 weeks
● E. 1 month
A. 5 days
Recommended transfusion criteria for cryoprecipitate include all except?
● A. Hemophilia A
● B. Von Willebrand’s disease
● C. Documented fibrinogen/factor VIII deficiency
● D. Documented disseminated intravascular coagulation (DIC)
● E. Anemia
E. Anemia
Regarding routine monitoring for rivaroxaban:
● A. PT daily
● B. aPTT daily
● C. INR on alternate days
● D. Bleeding time
● E. No monitoring required
E. No monitoring required
For reversal of clopidogrel for emergency surgery, platelets may be given. But in cases with continued oozing in the first day or so after discontinuing clopidogrel, which of the following regimen can be started?
● A. Activated factor I
● B. Activated factor V
● C. Activated factor VII
● D. Activated factor XII
● E. Activated factor XIII
C. Activated factor VII
Treatment with which of the following is associated with Coumadin necrosis during the initial days?
● A. Heparin
● B. Warfarin
● C. Massive transfusion
● D. Aspirin
● E. Clopidogrel
B. Warfarin
What is a common side effect with chronic use of heparin?
● A. Osteoporosis
● B. Heparin-induced thrombocytopenia
● C. Blindness
● D. Ototoxicity
● E. Hypothyroidism
A. Osteoporosis
For reversal of heparin, what should be given to the patient?
● A. Packed red cell concentrate
● B. Protamine sulphate
● C. Steroids
● D. Vitamin K
● E. Triofiban
B. Protamine sulphate
What is the test of choice for diagnosis of pulmonary embolism?
● A. Contrast-enhanced CT of the chest
● B. Postcontrast MRI of the chest
● C. Ultrasound of the chest
● D. Urinary fat globules
● E. Arterial blood gases
A. Contrast-enhanced CT of the chest
For treatment of pulmonary embolism, heparin is started. For an average 70 kg patient, begin with 5000 to 7500 unit IV bolus, followed by 1000 U/hour drip, and it is titrated by following what?
● A. PT
● B. aPTT
● C. INR
● D. Serum heparin levels
● E. Platelets coun
B. aPTT
An adult patient on aspirin comes in neurosurgical emergency with chronic subdural hematoma. He has reduced platelet count as well. Typical dosage of platelets for thrombocytopenic bleeding in adults is 6 to 10 U (where 1 U increases platelet count by 5k to 10k). All of the following are indications of platelet transfusion in a patient except?
● A. Platelet count (PC) less than 10k even if no bleeding
● B. PC less than 20k and bleeding
● C. PC less than 30k and the patient at risk of bleeding; for example, formation of petechiae, continuous bleeding from wound
● D. PC less than 50 and major surgery planned within 12 hours
● E. Patient on aspirin whose surgery can be postponed for 5 days
E. Patient on aspirin whose surgery can be postponed for 5 days
A patient on warfarin presented in neurosurgical emergency after road traffic accident. His CT of the brain showed extradural hematoma. On baseline investigations PT, APTT, and INR come out to be deranged. Which of the following are indications of transfusion of fresh frozen plasma (usual dosage of 2 bags equal to 400–600 mL) in a patient?
● A. PT > 18 sec, APTT > 55 sec or INR > 1.6
● B. Previous history of coagulation factor deficiency; for example, factor 2, 5, 7, 10, 11, or 12
● C. Patient taking warfarin and needs emergent surgery
● D. Deficiency of antithrombin 3, protein C, or protein S
● E. All of the above
E. All of the above
Use of warfarin during pregnancy can cause spontaneous abortion and stillbirth. Its use during the first trimester can also cause fetal warfarin syndrome which includes all of the following except?
● A. Scoliosis
● B. Polydactyly
● C. Vertebral column calcifications
● D. Ventriculomegaly
● E. Agenesis of corpus callosum
B. Polydactyly
All of the following are contraindications to full anticoagulation with heparin except?
● A. Recent severe head injury
● B. Recent craniotomy
● C. Hemorrhagic infarction
● D. Uncontrollable hypertension
● E. Intracranial hypertension due to sinus thrombosis
E. Intracranial hypertension due to sinus thrombosis
A diabetic elderly woman on low-molecular-weight heparin had to undergo an orthopedic procedure at bilateral hip joint. She was given spinal anesthesia for this purpose. After surgery she was given NSAIDs for pain control. The patient developed paralysis of lower limbs after surgery. What can be the possible
cause of this?
● A. Damage to bilateral sciatic nerve during surgery
● B. Damage to cord due to wrong-level spinal injunction
● C. Spinal shock due to cord damage during spinal anesthesia
● D. Spinal epidural hematoma
● E. None of the above
D. Spinal epidural hematoma
