Neurology - Epilepsy Drugs Flashcards

1
Q

What is the mechanism of phenytoin

A

Increase Na channel inactivation

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2
Q

What is phenytoin first line for

A

Tonic clonic

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3
Q

What is the mechanism of carbamazepine

A

Increase Na channel inactivation

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4
Q

What is carbamazepine first line for

A

Simple partial
Complex partial
Tonic clonic
Trigeminal neuralgia

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5
Q

What is the mechanism of phenobarbital

A

Increase GABA-A action

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6
Q

What is phenobarbital first line for

A

First line in children for:
Simple partial
Complex partial
Tonic clonic

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7
Q

What is the mechanism of valproic acid

A

Increase Na channel inactivation

Increase GABA concentration

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8
Q

What is valproic acid first line for

A

Tonic clonic

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9
Q

What is the mechanism of ethosuximide

A

Blocks thalamic T-type Ca channels

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10
Q

What is ethosuximide first line for

A

Absence

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11
Q

What is the mechanism of benzodiazepines

A

Increase GABA-A action

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12
Q

What are benzodiazepines first line for

A

Acute status epilepticus

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13
Q

What is used for prophylaxis for status epilepticus

A

Phenytoin

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