Neurology Flashcards
What drugs are used for essential tremor?
Beat blockers: propaolol and anticonvulsant: topiramate
What drugs are use in Parkinson’s Disease
L-dopa (decarboxylation of levodopa markedly increases the concentration of dopamine), amantadine (drug-induced extrapyrimadal side effects), selegeline and rasagaline (monoamine oxidase inhibitor (MAOI) that works by increasing the amount of dopamine in the brain), ropinirole and pramipexole (dopamine agonists), benzhexol (anticholinergic used in tremor dominant disease-side effects:memory disturbance and GI disturbance)
In what bacterial meningitis would a lymphocyte predominant CSF pattern be seen?
Listeria
Infarcts and visual field defects
Parietal- inferior homonymous quadrantopia
Temporal- superior homonymous quadrantopia
What type of tremor is cerebellar tremor
Intention tremor
What is another name for Pick’s Disease?
Frontotemporal dementia
Wernicke’s encephalopathy vs Korsakoff syndrome
Korsakoff syndrome is an abnormal mental state in which memory and learning due to nutritional deficiency in thiamine seen in alcohol dependence
Wernicke’s encephalopathy presents with confusion, ataxia, nystagmus and ophthalmoplegia
Retrograde vs antegrade amnesia
Anterograde amnesia
People with anterograde amnesia can’t form new memories, but they can still remember things from before they developed amnesia. Symptoms include forgetting conversations or events shortly after they happen, or forgetting the names and faces of people they met.
Retrograde amnesia
People with retrograde amnesia can’t recall memories from their past, including facts and general knowledge that they learned before the onset of amnesia. Symptoms include not being able to remember names, faces, places, dates, and other facts.
What is syringomelia?
Development of a cyst in the spinal cord. Can be post-traumatic. present with central cord syndrome involving the anterior horn (lower motor neurons), spinothalamic tract (pain and temperature), dorsal tracts are usually spared but may become involved
Types of seizures and presentation
Frontal lobe- prominent motor signs, speech arrest and dystonic posturing, laughing, crying
Parietal lobe- somatosensory phenomena
Occipital lobe- visual hallucinations
Temporal lobe- most common type of partial seizures. Staring, lip smacking and period of disorientation
Brainstem-myoclonus
Wallenburg Syndrome
Ischemia in Posterior inferior cerebellar artery leading to decreased sensation to ipsilateral half of face and contralateral limbs, ipsilateral Horner’s syndrome, ipsilateral weakness of the soft palate and pharynx, rotatory vertigo
Basilar artery stroke
motor and bulbar symptoms
Internal Carotid stroke
transient monocular blindness, hemodynamically variable symptoms
What does a basophilic adenoma produce?
ACTH, TSH, LH, FSH
Where is a craniopharyngioma located?
Craniopharyngiomas most frequently arise in the pituitary stalk and project into the hypothalamus. he most common presenting symptoms are headache (55–86%), endocrine dysfunction (66–90%), and visual disturbances (37–68%). Headache is slowly progressive, dull, continuous, and positional; it becomes severe in most patients when endocrine symptoms become obvious.