Hematology and Oncology Flashcards

1
Q

Sickle cell disease

A

valine is substituted for glutamic acid (glutamate) at position 6 of the beta global chain

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2
Q

Hereditary spherocytosis

A

defect of spectrum and ankyrin

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3
Q

Ret pro-oncogene causes what thyroid cancer

A

Medullary thyroid cancer. Chromosome 10

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4
Q

What red cell antigen leads to entry of P.vivax

A

Duffy

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