Neurology Flashcards

1
Q

Antiepileptic drugs can be stopped if seizure free for …[a]…, with the AEDs being stopped over {B duration]

A

A - > 2 years

B - 2-3 months

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2
Q

Parietal lobe lesions features (5)

A
  • sensory inattention
  • apraxia (inability to perform learned movements, understanding is unaffected)
  • astereognosis (tactile agnosia)
  • inf homonymous hemianopia
  • Gerstmanns - alexia, acalculia, finger agnosia, right-left disorientation
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3
Q

Occipital Lobe lesions (3)

A
  • contralateral homonymous hemianopia (with macular sparing)
  • cortical blindness
  • visual agnosia
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4
Q

Temporal lobe lesions features (4)

A
  • Wernicke’s receptive aphasia
  • Superior homonymous hemianopia
  • Auditory agnosia
  • Prosopagnosia (difficulty to recognise faces)
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5
Q

Frontal lobe lesions features (5)

A
  • Broca’s expressive aphasia
  • disinhibition
  • perseveration (repetitive and continuous behaviours)
  • anosmia (loss of smell)
  • inability to generate list
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6
Q

Specific area lesions below, provide their associated conditions…

a) Medial thalamus and mammillary bodies of the hypothalamus
b) Subthalamic nucleus of the basal ganglia
c) Striatum (caudate nucleus) of the basal ganglia
d) Substantia nigra of the basal ganglia
e) Amygdala

A

a) Wernicke and Korsakoff syndrome
b) Hemiballism - involuntary ipsilateral hyperkinetic movements
c) Huntington chorea
d) Parkinson’s disease
e) Kluver-Bucy syndrome (hypersexuality, hyperorality, hyperphagia, visual agnosia

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7
Q

Lateral medullary syndrome

a) lesion
b) features (3)

A

a) PICA - post inf cerebella artery

b) cerebellar signs, contralateral sensory loss, ipsilateral horners

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8
Q

Restless leg syndrome management (4)

A
  1. Walking, stretch, massage
  2. Treat Fe Def anaemia
  3. Dopamine agonist - ropinerole
  4. Benzo
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9
Q

Subacute combined degeneration of spinal cord is
A) what deficiency
B) where is lesion
C) features

A

A) b12 Def eg in alcoholics
B) lateral corticospinal and dorsal column
C) UMN signs with reduced proprioception and vibration

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10
Q

Normal pressure encephalopathy triad

A

Urinary incontinence
Gait abnormality
Dementia

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11
Q

Clutser headache management

A
  1. 100% O2 + SC sumatriptan

2. Verapamil for prophylaxis

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12
Q

BPPV
Ix
Mx

A

Dix-Hallpike manoeuvre is diagnostic

Epley manoeuvre is for treatment

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13
Q

Rinne + Weber test

A

Conductive hearing loss Bone conduction > air conduction in affected ear
Air conduction > bone conduction in unaffected ear Lateralises to affected ear
Sensorineural hearing loss Air conduction > bone conduction bilaterally Lateralises to unaffected ear

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14
Q

Pyridostigmine MOA

A

long acting acetylcholinesterase inhibitor

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15
Q

Bells’ palsy association (1)

A

hyperacusis

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16
Q

Dystrophia myotonica - DM1 (myotonic dystrophy)

features (4)

A
distal weakness initially
autosomal dominant
diabetes
dysarthria
slow releasing grip
17
Q

Lambert eaton myasthenic syndrome
assocation
antibody

A

small cell lung ca (breast + ovarian)

anti - voltage gated calcium channel

18
Q

Internal ophthalmoplegia is due to lesion in the…
features (2)
Association

A

medical longitudinal fasciculus
F - ipsilateral adduction failure, contralateral nystagmus
A - multiple sclerosis

19
Q

Charcot-Marie Tooth (aka hereditary sensorimotor neuropathy. peroneal musclar atrophy)
Features

A

LMN and sensory signs in all limbs

hereditary

20
Q

von Hippel-Lindau syndrome

features

A

retinal haemorrahges
phaeochromocytoma
clear cell kidney ca

21
Q

Cluster headache
Mx (2)
prophylaxis (1)

A

100% oxygen, SC Triptan

verapamil

22
Q

Syringomyelia

Features

A

cape-like loss of pain and termperature, weakness

spinothalamic tract + corticospinal tract

23
Q

Chiari Malformation association

A

Syringomyelia

24
Q

Brain abscess
CT finding
Mx

A

single ring-enhancing lesion

IV Ceftriaxone + Metro

25
Q

SAH LP after how long?

A

12 hours

26
Q

Autosomal Dominant polycystic kidney disease protein

A

polycystin

27
Q

Medullary sponge syndrome association

A

renal stones
recurrent UTI
assymptomatic bacturia

28
Q

Rapidly progressive glomerulonephritis
Features (3)
Mx

A

F - Anti GBM Ab, glomerulonephritis (protein/ haematuria), pulmonary haemorrhage
Mx - prednisolone

29
Q

Renal tubular acidosis Type 1

A

sjogrens
SLE
Hypokalaemia

30
Q

Renal tubular acidosis type 4

A

chronic kidney disease

hyperKalaemia