Dermatology Flashcards
Drug causes of Steven Johnson syndrome (5)
penicillin sulphonamides anti epileptics - lamotrigine, carbamazepine, phenytoin allopurinol NSAIDs oral contraceptive pill
Renal transplant associated cancer (1)
skin cancer (particularly squamous cell) is the most common malignancy secondary to immunosuppression
Contact Dermatitis (2) types and examples
1 - Irritant - non allergy, usually hands, eg detergents
2 - allergic - type IV hypersensitivity, weeping eczema eg hair dyes
Lichen planus (autoimmune condition against keratinocytes) rash
- description and site
- Mx
Itchy, raised - ankles/ soles, wrists/ palms, lower back
Mx - topical steroid, Benzydamine (if oral involvement)
Blisters/ bullae differentiation (whether mucosal involvement) (2)
no mucosal involvement: bullous pemphigoid
mucosal involvement: pemphigus vulgaris
Dermatitis herpetiformis (IgA)
rash description
association (1)
Mx
itchy, vesicular lesions on extensor surfaces
associated with coeliacs
Mx - dapsone, gluten free diet
Lichen sclerosis
Rash description
Mx
elderly, genitalia, white patches, itch
Mx - topical steroid + emollients
Increased risk vulva cancer
Fungal nail infections
Mx - Dermatophyte, Candida
Dermatophyte - oral terbinafine/ oral itraconazole alternative
Candida - topical antifungal (eg Amorolfine)
Pompholyx eczema
location of rash
effects hands and feet
Pityriasis Vesicolour
fungal cause
rash description
Mx
Malassezia furfur
trunk, hypopigmented, scales
Mx - topical antifungal (ketoconazole shampoo)
Pellagra features (3)
dementia
diarrhoea
dermatitis
facial hirsutism Mx (1)
Topical eflornithine
Scabies Mx
1st - Permethrin: all skin including scalp + leave for 12 hours + retreat in 7 days
2nd - Malathion
Rosacea Mx
mild
severe
mild/moderate: topical metronidazole
severe/resistant: oral tetracycline
Psoriasis (primary care) Mx (3 steps)
1st - topical corticosteroid + topical vit D analogue OD 4 weeks
2nd (>8weeks no improvement): vit D analogue BD
3rd - topical corticosteroid BD OR a coal tar preparation OR dithranol