Dermatology Flashcards

1
Q

Drug causes of Steven Johnson syndrome (5)

A
penicillin
sulphonamides
anti epileptics - lamotrigine, carbamazepine, phenytoin
allopurinol
NSAIDs
oral contraceptive pill
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2
Q

Renal transplant associated cancer (1)

A

skin cancer (particularly squamous cell) is the most common malignancy secondary to immunosuppression

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3
Q

Contact Dermatitis (2) types and examples

A

1 - Irritant - non allergy, usually hands, eg detergents

2 - allergic - type IV hypersensitivity, weeping eczema eg hair dyes

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4
Q

Lichen planus (autoimmune condition against keratinocytes) rash

  • description and site
  • Mx
A

Itchy, raised - ankles/ soles, wrists/ palms, lower back

Mx - topical steroid, Benzydamine (if oral involvement)

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5
Q

Blisters/ bullae differentiation (whether mucosal involvement) (2)

A

no mucosal involvement: bullous pemphigoid

mucosal involvement: pemphigus vulgaris

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6
Q

Dermatitis herpetiformis (IgA)
rash description
association (1)
Mx

A

itchy, vesicular lesions on extensor surfaces
associated with coeliacs
Mx - dapsone, gluten free diet

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7
Q

Lichen sclerosis
Rash description
Mx

A

elderly, genitalia, white patches, itch
Mx - topical steroid + emollients
Increased risk vulva cancer

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8
Q

Fungal nail infections

Mx - Dermatophyte, Candida

A

Dermatophyte - oral terbinafine/ oral itraconazole alternative
Candida - topical antifungal (eg Amorolfine)

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9
Q

Pompholyx eczema

location of rash

A

effects hands and feet

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10
Q

Pityriasis Vesicolour
fungal cause
rash description
Mx

A

Malassezia furfur
trunk, hypopigmented, scales
Mx - topical antifungal (ketoconazole shampoo)

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11
Q

Pellagra features (3)

A

dementia
diarrhoea
dermatitis

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12
Q

facial hirsutism Mx (1)

A

Topical eflornithine

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13
Q

Scabies Mx

A

1st - Permethrin: all skin including scalp + leave for 12 hours + retreat in 7 days
2nd - Malathion

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14
Q

Rosacea Mx
mild
severe

A

mild/moderate: topical metronidazole

severe/resistant: oral tetracycline

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15
Q

Psoriasis (primary care) Mx (3 steps)

A

1st - topical corticosteroid + topical vit D analogue OD 4 weeks
2nd (>8weeks no improvement): vit D analogue BD
3rd - topical corticosteroid BD OR a coal tar preparation OR dithranol

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16
Q

Psoriasis (secondary care) Mx

A

Phototherapy - UVB

Oral methotrexate/ Ciclosporin

17
Q

Causes of erythema nodosum (4)

A

infection - streptococci, Tb
disease - sarcoidosis, Crohns, Behcet’s, malignancy/lymphoma
drugs - penicillin, sulphonamides, COCP
pregnancy

18
Q

Actinic keratoses Mx

A

Topical Flurouricil

19
Q

Acanthosis Nigricans Cancer association

A

Gastric cancer

20
Q

Impetigo Mx

A

1 - Hydrogen peroxide cream 1%
2 - Topical Fusidic acid
3 - Topical Mupirocin
4 - Oral flucloxacillin

21
Q

Eczema Herpeticum (HSV 1+2)
Features
Mx

A

bg of eczema, rapidly progressive painful rash

Mx - IV Aciclovir

22
Q

Bullous pemphigoid Ix

A

skin biopsy