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MRCP > ID > Flashcards

ID Flashcards

1
Q

Tetracycline common side effect (1)

A

Photosensitivity

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2
Q

Nematodes (eg lava migrans) Management (2)

A

Thiabendazole

Albendazole

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3
Q

Tetanus management (3)

A

Supportive ventilation - support and muscle relaxants
IM tetanus immunoglobulin - for high risk wounds
Metronidazole

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4
Q

Syphilis is caused by what organism?

A

Treponema pallidum

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5
Q

Strongyloides stercoralis
Features (3)
Management (2)

A

A) papulovesicular rash soles feet and buttocks, Abdo pain, diarrhoea
B) ivermectin, albendazole

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6
Q

Diphtheria
Features(4)
Management (2)

A

A) sore throat, grey appearance tonsils , bulky lymphadenopathy, heart block
B) penicillin, antitoxin

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7
Q

Penile ulcers
A) painful
B) painless

A

A) chancroid (single,deep, lymphadenopathy), herpes (multiple, superficial, nil lymphadenopathy)

B) syphilis

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8
Q

Leptospirosis Mx

A

Doxy or benpen

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9
Q

Chickenpox in pregnancy management
A) if nil immunity
B) if symptomatic

A

A) Varicella zoster Ig - VZIG

B) aciclovir

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10
Q

Damgue fever
Features (5)
Management

A 
A) Retro orbital headache 
Rash (maculopapular)
Fever
Thrombocytopenia
Leukopenia

B) supportive measures

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11
Q

Lyme disease
A) features - i) early ii) late
B) investigation
C) management

A

A) erythema migrans “bulls eye” rash, headache fevers, lethargy
Late: heart block, facial nerve palsy, meningitis
B) Elisa test - borrelia burgdorferi
C) Doxycycline if early, ceftriaxone if severe

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12
Q

Lyme disease
A) features - i) early ii) late
B) investigation
C) management

A

A) erythema migrans “bulls eye” rash, headache fevers, lethargy
Late: heart block, facial nerve palsy, meningitis
B) Elisa test - borrelia burgdorferi
C) Doxycycline if early, ceftriaxone if severe

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13
Q

Severe features of malaria (7 Inc complications)

A 
Acidosis 
Parasitemia >2%
Shizonts on blood film
Hypoglycaemia 
Temp >39
Severe anaemia 
Complications - cebebral malaria, renal failure, ARDS, DIC
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14
Q

Leprosy
A) features (2)
B) Mx (3)

A

A) hypopigmented skin lesions, sensory neuropathy

B) rifampicin, clofazimime, dapsone

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15
Q

Leprosy
A) features (2)
B) Mx (3)

A

A) hypopigmented skin lesions, sensory neuropathy

B) rifampicin, clofazimime, dapsone

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16
Q

Measles
Features (5)
Mx

A

A) koplick spots - white spots on buccal mucosa
Rash on face, coryza, conjunctivitis, fever

B) supportive, inform public health

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17
Q

Inactived vaccines (3)

A

Hepatitis A
Influenza
Rabies

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18
Q

Toxins vaccines (3)

A

Pertussis
Tetanus
Diphtheria

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19
Q

Conjugate vaccines - links the poorly immunogenic bacterial polysaccharide outer coats to proteins to make them more immunogenic (5)

A 
Pneumococcus
Meningicoccus
Hepatitis b 
Haemophillis 
Human pappilovirus
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20
Q

Gonorrhea (gram neg diplococcus) management

A

IM ceftriaxone stat

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21
Q

Shigella Mx

A

Self limiting

If severe, immunocompromised- ciprofloxacin

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22
Q

HIV, neuro symptoms, single brain lesions with homogenous enhancement

A

CNS lymphoma

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23
Q

Tetanus Mx post wound
A) fully vacc < 10 years
B) fully vacc > 10 years or never been vacc

A

A) no Vax or If
B) low risk wound - booster
High risk wound - Ig + booster

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24
Q

Ando pain, diarrhoea, streaky rash ? And Mx

A

Strongyloides

Ivermectin

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25
Q

Non specific (non gonococcal) urethritis Mx

A

1 week doxy

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26
Q

Non specific (non gonococcal) urethritis Mx

A

1 week doxy

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27
Q

Anthrax (painless black scab, lymphadenopathy) Mx

A

Ciprofloxacin

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28
Q

Lyme disease Mx
Early
Late

A

A) doxy

B) iv ceftriaxone

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29
Q

Following treatment for syphilis: TPHA remains ?, VDRL becomes ?

A

Successful treatment for syphillis
TPHA - positive
VDRL - negative

30
Q

mycoplasma pneumonia
features (1)
chest x ray (1)
Ix (1)

A

erythema multiforme - “target lesions”
bilateral consolidation
Serology

31
Q

pelvic inflammatory disease Mx

A

ofloxacin + metronidazole

32
Q

Genital warts Mx (3)

A

Single - cryotherapy
Multiple - Topical Podophyllum
3rd line - Topical Imiquimod

33
Q

Schistosomiasis Mx

A

Praziquantel

34
Q

Active Tb Mx

A

first 2 months - RIPE - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol
continuation - Rifampicin, isonazid

35
Q

Latent Tb Mx

A

3 months Isonazid + Rifampicin OR 6 months isoniazid

36
Q

Renal infection + fever = ?

A

Cytomegalovirus

37
Q

Mycobacterium avium complex Mx
A) prophylaxis (CD4 <100)
B) Mx (normally CD4 <50)

A

A) clarithromycin or azithromycin

B) rifampicin, ethambutol + clarithromycin

38
Q

Chlamydia Mx
A) normal
B) pregnancy

A

A) Doxycycline

B) if pregnant - azithromycin or amoxicillin

39
Q

Nucleoside analogue reverse transcriptase inhibitors (NRTI)
A) example
B) mechanism
C) common s.e

A

A) “ine”, zidovudine, abacavir, tenofovir
B) prevent synthesis of dsViral DNA
C) peripheral neuropathy

40
Q

Non nucleoside reverse transcriptase inhibitors (NNRTI)
A) example
B) mechanism
C) side effects

A

A) nevirapine, efavirenz (vir in middle)
B) viral reverse transcriptase
C) rash, p450 inducer

41
Q

Protease inhibitor (PI)
A) examples
B) mechanism
C) side effects

A

A) “navir” ending
B) bind viral protease prevent viral replication
C) p450 inhibitor, metabolic syndrome

42
Q

Integrase inhibitor
A) example
B) mechanism
C) side effects

A

A) “gravir” ending

B) prevents viral DNA from being inserted into host genome

43
Q

Cat scratch disease organism

A

Bartonella henselae

44
Q

Epiglottis bacteria

A

Haemophillis influenzae

45
Q

Campylobacter Mx (2)

A
  1. supportive

2. Clarithromycin (if severe, eg >8 bloody stools/ day)

46
Q

Live attenuated Vaccines (should not be given to immunocomprismised) (6)

A 
Yellow fever
Oral polio
Intranasal influenza
Varicella
Measles, mumps and rubella (MMR)
Tb (BCG)
47
Q

Chlamydia Mx

A

Doxycycline

48
Q

Gingivostomatitis (oral ulcers) cause

A

Herpes simplex

49
Q

Pneumocystitis jiroveci pneumonia Mx

A

Co-trimoxazole

50
Q

Toxoplasmosis Mx

A
  1. Immunocompetent - self resolve

2. Immunocompromised - Pyrimethamine + sulphadiazine

51
Q

Primaquine MOA

A

used in non-falciparum malaria to destroy liver hypnozoites and prevent relapse

52
Q

Most common viral meningitis cause

A

Coxsackie

53
Q

Lyme disease Mx (2)

A

Doxycycline (amoxicillin if pregnant)

Ceftriaxone in disseminated disease

54
Q

Leprosy Mx
A) >6 lesions
B) <6

A

A) rifampicin, dapsone and clofazimine for 12 month

B) rifampicin and dapsone for 6 months.

55
Q

Chagas disease
parasite
association
Mx

A

Trypanosoma cruzi
Dilated cardiomyopathy
Benznidazole

56
Q

Leptospirosis
Association
Ix
Mx

A

Sewage, farmer, abbatoir
Serology
Benpen/ doxy

57
Q

Gonorrhoea
Ix
Mx

A

Microscopy: Gram neg diplococcus

Ceftriaxone

58
Q

URTI + Amoxicillin = Rash

?cause

A

Infectious Mononucleosis

59
Q

Shigella Mx

A

Self resolve

Ciprofloxacin

60
Q

Genital ulcers cause?

a) painful
b) painless

A

Painful: Herpes > Chancroid
Painless: Syphilis > Lymphogranuloma Venerum

61
Q

Amoebiasis Mx

A

Metronidazole (+ diloxanide, if invasive)

62
Q

African trypanosomiasis (sleeping sickness) Mx

A

Pentamidine

63
Q

Campylobacter Mx

A

Clarithromycin

64
Q

Listeria Mx

A

Amoxicillin (+ Gentamicin, if meningitis)

65
Q

post exposure prophylaxis Hepatitis B

A

a) fully vaccinated - booster

b) not fully vaccinated - HBIG + booster

66
Q

Human/ Animal bites Mx

A

co-amox

67
Q

Chickenpox Mx in pregnancy

A

1st - check antibodies

2nd

a) immune
i) <20 weeks - consider aciclovir with caution
ii) >20 weeks + rash <24hours = aciclovir

b) not immune
i) <20 weeks - VZIG
ii) >20 weeks - VZIG/ aciclovir

68
Q

When to start antiretrovirals and PJP prophylaxis in HIV

A

ARV - ASAP

PJP - CD4 <200

69
Q

Cat scratch disease organism

A

Bartonella henselae

70
Q

Chronic hepatitis b treatment

A

Entecavir

71
Q

post splenectomy infections

A

strep pneumoniae
neiserria meningitidis
H influenzae

MRCP (14 decks)

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