Neurobiology of Cognition

Question 1

describe fluent aphasia

Answer 1

the patient speaks articulately and fluently but their ability to follow the line of questioning is impaired

Question 2

describe broca’s aphasia

Answer 2

understand questions but can’t articulate what they want to say

Question 3

organic causes of amnesia

Answer 3

alzheimers
vascular
korsakov’s psychosis
parkinson’s

Question 4

diagnostic criteria for dementia

Answer 4

cognitive impairment
progression
>6 months
significant impairment in functions
not caused by a comorbidity

Question 5

memory loss is always the main symptoms in dementia T or F

Answer 5

F, can be preceded by cognitive impairment etc

Question 6

what is memantine?

Answer 6

NMDA receptor antagonist

Question 7

for what condition is memantine given?

Answer 7

advanced dementia with behaviour disturbance

Question 8

a PET scan would flag upin dementia T or F

Answer 8

T due to presence of amyloid

Question 9

amyloid beta is __ in CSF of someone with dementia T or F

Answer 9

T

Question 10

emotions exists in what part of the brain?

Answer 10

limbic brain

Question 11

fight/flight response originates in the…

Answer 11

limbic brain

Question 12

if you lose function in the frontal lobe what part of the brain takes over?

Answer 12

limbic brain

Question 13

a lesion in the dorsolateral frontal cortex will cause what personality changes changes?

Answer 13

apathetic, withdrawn, disorganised patient;
can mistake for depression
consider frontotemporal dementia

Question 14

Tx of wernickes encephalopathy

Answer 14

thiamine replacement

Question 15

examples alcohol related brain damage?

Answer 15

wernickes encephalopathy
korsakoff syndrome
myelin sheath degradation
neuroinflammation
fall -> SDH