Management of Opiate Misuse Flashcards
heroin has a ___ half life
short
2 main constituents of opium
morphine
codeine
what do you add to morphine to get heroin?
add 2 acetyl rings to the morphine molecule
medical term for snorting?
insufflation
why does heroin cross the BBB easily?
due to its 2 acetyl groups
heroin is metabolised to ___ in the body
morphine
if you do a drug screen and you detect 6-mono-acetylmorphine what does this mean?
indicative of recent definite heroin use
if you do a drug screen and detect morphine, what does this mean?
the patient could have had either codeine or heroin as both metabolise to morphine
effect of heroin?
initial euphoria analgesia respiratory depression bradycardia and hypotension pupillary constriction constipation
what is gouching?
nodding off due to drowsiness
why can teeth look in bad condition in heroin addicts?
depressed salivary production
increased analgesia so cant feel toothache
withdrawal symptoms typically occur between _ to _ hours
6-8 hours
how often do heroin addicts use the drug per day?
3
withdrawal symptoms from heroin?
dysphoria cravings agitation tachycardia and hypertension diarrhoea/N+V piloerection join pains dilated pupils yawning runny nose/watery eyes
local complications of IV drug use?
cellulitis
abscess
thrombophlebitis
NF