Neuro_Exam 1_Basal Gang

Question 1

striatum wants to _____

Answer 1

inhibit GPE

Question 2

GPE wants to _______

Answer 2

inhibit sub stalamus

Question 3

subthalamus wants to ______

Answer 3

activate GPI

Question 4

Dopamine acts on _____ to _____

Answer 4

D1 D2 to decrease EPI

Question 5

subthalamus ______ to increase movement

Answer 5

activates subnigra to release dopamine to D2 or D1

Question 6

D1 activated by the chemical

Answer 6

substance P (d block, styles p)

Question 7

D2 activated by the chemical:

Answer 7

enkaphelin (incas-fell-in during hunting season) first neurons to die during hunting season

Question 8

______ excite D2 neurons

Answer 8

cholinergic interneurons

Question 9

_______ inhibits ach

Answer 9

muscarinic anticholinergic

Question 10

____ is a disease involving ____ nuc lesion

Answer 10

hemiballisim, subthalamic nuc lesion. less appetite for Gooseberry pie (Gpi)

Question 11

_____ involves death of enkaphelin

Answer 11

huntington’s disease

Question 12

substantia nigra r____ contains _______ neurons that project to the ______

Answer 12

reticulata, GABArgic, thalamus and brainstem

Question 13

substantia nigra c ______, contains _____ that project to the ______

Answer 13

pars compacta, dopaminergic, striatum

Question 14

In healthy people, ______ neurons accumulate ______ giving the _____ a _____ color; in parkinsons, you see a loss of ____ showing a ____

Answer 14

dopamine, melanin, snc, dark, pigmentation, dopamine

Question 15

_______ interneurons predominantly excite the _____, this balances the _______

Answer 15

cholinergic, indirect pathway, inhibitory effect of dopamine

Question 16

________ can ameliorate ______ of PD

Answer 16

muscarinic anticholinergics, akinesia

Question 17

lesions of basal ganglia causes ______, the two groups are :

Answer 17

dyskinesias: hyperkinetic (temor, ballism, chorea, tics) hypokinetic (rigidity, bradykinesia, akinesia)

Question 18

huntingtons mnemonic:

Answer 18

Then hunting season caused an indirect (pathway D2) death of straight Korean (chorea) men (striatum) and it was the Incas who first fell in the trap (Enka-fell-in: first neurons to die)

Question 19

parkinsons mnemonic:

Answer 19

In the Park where Brady kind of used to play, there seemed to be a decrease in the directions, and it all made me indirectly increased my hunger for Gooseberry Pie;

Question 20

hemiballism mnemonic:

Answer 20

Hemi (semi) Bollywood dancer rode a unicycle up a ladder to the lama subway (subway of lamas instead of train cars) and they were no longer inhibited; This eventually caused a decreased in excitement for Gooseberry Pie (GPI)

Question 21

___ and ____ are additional movement disorders

Answer 21

essential tremor, rigidity

Question 22

______ are caused by ______ lesions and never change

Answer 22

rigidity, basal gang with lead pipes, and cop wheels

Question 23

______ are a resistance that varies with speed, ____ deep tendon reflex, _____ tone,

Answer 23

spasticity, clasped knife, clonus