Neuro Flashcards

1
Q

Medications that may cause pseudo tumor

A

Vit a
Steroids (also treat it)
Thyroxine
Lithium

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2
Q

Cushing’s triad

A

Hypertension, bradycardia, abnormal respirations

Late findings of increased ICP and usually indicate impending herniation

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3
Q

Neonates with cranial bruit, hydrocephalus and Hx of CHF

A

Vein of Galen malformation

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4
Q

Medications that cause ataxia

A

Anticonvulsants
Alcohol
Thallium

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5
Q

Malignancies associated with ataxia telangiectasia

A

Hodgkin lymphoma and leukemia

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6
Q

Clinical features of friedreich ataxia

A

Elevated plantar arch

Absence of lower extremity deep tendon reflexes

Cardiomyopathy leading to CHF

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7
Q

What is the most common malignant brain tumor of childhood

A

Medulloblastoma (infra tentorial)

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8
Q

What percentage of the time are optic nerve gliomas associated with neurofibromatosis

A

25 percent

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9
Q

Presentation of acute transverse myelitis

A

Fever and sudden onset of paralysis

Increased tone and hyperreflexia

Respiratory arrest or compromise is the main consequence of concern

CSF has increased polys and a negative gram stain

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10
Q

Werdnig-Hoffman disease

A

Presents in infancy as severe hypotonia, weakness and tongue fasciculations

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11
Q

What do you think of in a pt that presents with areflexia and what can it be due to

A

Guillian barre syndrome

Viruses and campylobacter jejuni

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12
Q

What lab finding is always elevated in kids with duchenne even before weakness appears and also in female carriers

A

CPK

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13
Q

Myotonic muscular dystrophy vs duchenne’s

A

X linked dominant vs recessive
Normal CPK vs elevated
Distal muscle weakness vs proximal

Both striated and smooth muscle are affected

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14
Q

Ramsay hunt syndrome

A

Facial weakness associated with pustular lesions, ear pain and taste loss

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15
Q

Bell’s palsy involved what part of the face

A

Whole face! Upper and lower

If upper spared think of upper motor neuron injury such as with stroke

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16
Q

Risk factors for CP in full term infants

A

Advanced maternal age, black race, IUGR

17
Q

Risk factors for recurrence of febrile seizures

A

A low fever at time of seizure
Short period of time btw fever and seizure
Young age
Family Hx of febrile seizure

18
Q

Tx of absence seizures

A

Ethosuximide

19
Q

Presentation of juvenile myoclonic epilepsy

A

Myoclonic jerks upon awakening
Generalized tonic-clonic
Absence sz in 1/3 of pts

20
Q

What genetic condition is infantile spasms associated with

A

Tuberous sclerosis

21
Q

Difference between simple and complex partial seizures

A

With simple consciousness is maintained

22
Q

Treatment of simple partial seizures

A

Carbamazepine

23
Q

Benign Rolandic epilepsy

A

Most common form of partial epilepsy in childhood

Dominant trait

Associated with migraine headaches

Facial motor seizure and often unilateral sensory involvement

Pt is fully aware but unable to speak

Occur while the child is asleep at night

24
Q

ERG finding for Rolandic epilepsy

A

Biphasic focal centrotemporal spikes and slow waves

25
Q

Most common risk factor for premies developing CP

A

Perinatal infection

26
Q

Pt with a stroke, elevated lactate level and sensorineural hearing loss. Dx and best diagnostic step

A

Mitochondrial disorder

Molecular analysis of mitochondrial DNA