Derm Flashcards

1
Q

Buzz words (3) for neonatal herpes

A
  • clustered or grouped vesicles on an erythemarous base
  • multinucleated giant cells
  • eosinophilic intranuclear inclusions
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2
Q

Buzz words (3) for transient neonatal pustular Melanosis

A
  • multiple pustules, brown macules, vesicles and pustules on a NON erythematous base
  • PMNs WITHOUT bacteria
  • present at birth

Staphylococcus would have pmns with bacteria

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3
Q

What are the foods known to trigger eczema? (5)

A

Milk, eggs, soy, wheat, peanuts

Without allergy testing it is not recommended to eliminate the food.

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4
Q

Inflamed eczema that doesn’t respond to steroids or antibiotics would make you consider what diagnosis?

A

Eczema herpeticum

  • vesicles, punched out lesions and crusted erosions are buzz words
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5
Q

Eczema in an immunocompromised patient would make you think of?

A

Wiskott-Aldrich syndrome or hyperimmunoglobulin E syndrome

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6
Q

What 2 things are typical examples that cause allergic contact dermatitis?

A

Jewelry and poison ivy

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7
Q

This is a delayed hypersensitivity reaction that requires multiple exposures.

A

Allergic contact dermatitis

Vs. irritant there is no delay.

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8
Q

What type of reaction is poison ivy?

A

Type 4

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9
Q

Myths of poison ivy dispelled

A
  • exposure during the winter CAN cause a rash
  • exposure to aerosolized poison ivy CAN cause a rash
  • fluid from vesicles does NOT spread rash
  • rash is NOT contagious
  • NO desensitization treatments available
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10
Q

What is the auspitz sign and which which condition?

A

When plaques come off and leave behind bleeding spots the size of pins.

Psoriasis

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11
Q

What is the treatment for Ichthyosis vulgaris?

A

Keratokytic agents like ammonium lactate. Also alpha hydroxy acid and urea containing emollients.

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12
Q

Buzz word for granuloma annulare?

A
  • NON-SCALING! Annular lesión without epidermal involvement.
  • skin is intact
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13
Q

Buzzword for staphylococcal scalded skin syndrome

A

Separation of the skin in sheets

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14
Q

What are the triggers (2) for erythema multiforme minor?

A

HSV and medications

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15
Q

How is the rash from erythema multiforme major (aka Steven Johnson)

A

Similar to EM minor (target lesions) but spreads more quickly and progresses to involve mucous membranes.

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16
Q

What medications trigger erythema multiforme major?

A

Sulfa drugs, anticonvulsants and nsaids

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17
Q

How do you distinguish staph scalded skin from toxic epidermal necrolysis?

A

Biopsy
TEN involves the dermis

TEN usually older children

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18
Q

Buzz words for pyoderma gangrenosum

A

Boggy and blue ulcers with a necrotic base

19
Q

What is erythema chronicum migrans

A

Associated with Lyme disease. Bulls eye rash.

20
Q

What is erythema marginatum

A

Associated with rheumatic fever. Erythematous macule on the trunk that clears centrally.

21
Q

Treatment for scabies

A

Permethrin 5%

22
Q

What’s a clinical sign consistent with pubic lice

A

Maculae caerulae - blue-gray macules on the abdomen or inner thigh

23
Q

Thx for crabs in the eyelashes

A

Petroleum jelly

24
Q

How is papular urticaria different from scabies

A

Papular urticaria will be clustered eruthematous papules whereas scabies they will be linear not clustered.

Also no family members affected with papular urticaria

25
Q

What are the types of non inflammatory acne

A
Closed comedones (whiteheads)
Open comedones (blackheads)
26
Q

“Acne” that is unresponsive to tx would make you think of?

A

Adenoma sebaceum (angiofibroma)

27
Q

What medications can lead to acne?

A

Steroids, phenobarbital and phenytoin

28
Q

What are side effects of isotretinoin

A

Dry lips, dry skin, dry eyes, nosebleeds and headaches

29
Q

What other physical finding will you see in a pt with alopecia areata

A

Nail pitting

30
Q

What should patients with urticaria pigmentosa avoid?

A

Narcotic pain reliever, nsaids, aspirin, radiocontrast material

Because they release histamine **

31
Q

Treatment for tinea versicolor

A

Astringent or topical antifungal

May use oral ketoconazole, fluconazole, and itraconazole. Topical selenium sulfide

32
Q

What are the stages of the rash for incontinente pigmenti

A
  • blistering rash at birth: erythematous papules and vesicles in crops along the lines of blaschko that last 1-2 wks
  • swirls of warty growths
  • hyperpigmentation in a marble cake pattern in childhood
  • hypopigmentation in adulthood
  • pts may also have hair loss and eye/dental abnormalities
33
Q

How is incontinenta pigmenti inherited

A

X linked dominant

34
Q

In which side is glaucoma in pts with strurge Webber associated? Seizures?

A

Glaucoma - on same side as the port wine stain. Seizures on the contralateral side.

35
Q

Criteria for NF1 (8)? How many are required for diagnosis?

A
  • 6 or more cafe au lait spots >5mm wide
  • lisch nodules
  • neurofibromas
  • optic nerve glioma
  • inguinal and axillary freckling
  • bony defects
  • FMH if NF1 (first degree)

2

36
Q

Inheritance pattern of NF1

A

Autosomal dominant on chromosome 17

37
Q

What are associated conditions for kids with NF1 and what must you monitor?

A

Pheochromocytoma and renal artery stenosis. Monitor for hypertension.

38
Q

Inheritance of NF2

A

Autosomal dominant in chromosome 22

39
Q

Presentation of NF2

A

Hearing loss or tinnitus due to acoustic neuromas (schwannoma). May also present with ocular symptoms due to cataracts or hamartomas of the retina.

40
Q

Criteria for tuberous sclerosis (8). How many required for diagnosis?

A
  • more than 3 ash leaf spots
  • periventricular/cortical tubers (present as seizure)
  • sebaceous glands hyperplasia (adenomas described or shown in face do not confuse with acne)
  • shagreen patch (orange peel appearing skin)
  • sub/periungal fibroma
  • cardiac rhabdomyoma
  • retinal modular hamartomas
  • renal angiomyolipoma

2

41
Q

What is kasabach-merritt syndrome

A

Hemangioma that enlarged rapidly due to sequestration of platelets. Results in low platelet count and bleeding.

42
Q

What is darier sign and what condition is it associated with

A

Rubbing causes hives or bullae. Mastocytosis (urticaria pigmentosa)

43
Q

Risk factors for melanoma development in pediatric patients

A

White race, female gender, adolescent age group, immunodeficiency, solid organ transplant, childhood malignancy, the presence of xeroderma pigmentosum, dysplastic nevi, many melanocytic nevi, family history of melanoma.