Neural And Chemical Control Of Respiration Flashcards

0
Q

What part of the brain generates the basic thing rhythm?

A

The brainstem

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1
Q

The nervous system integration with the respiratory system is designed to maintain normal blood levels of….

A

Oxygen, carbon dioxide and hydrogen ions

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2
Q

What influences the brain stems control over the basic breathing rhythm?

A

Ventilatory reflexes

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3
Q

What controls respiratory rate and depth?

A

Blood gas concentrations and lung stretch receptors

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4
Q

What is the most important factor for control of respiratory drive at rest?

A

Arterial Pco2

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5
Q

What do central chemoreceptors detect?

A

Changes in arterial Pco2 ( via the H+ content of the CSF)

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6
Q

What do peripheral chemoreceptors detect?

A

Changes in arterial Po2, Pco2, pH

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7
Q

Where are the major peripheral chemoreceptors?

A

Aortic arch and carotid sinus

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8
Q

What makes up the central pattern generator in the medulla?

A

Dorsal respiratory group and the vernal respiratory group

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9
Q

Are inspiratory and expiratory neurons segregated from one another or intermingled?

A

Intermingled

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10
Q

Where does central pattern generator input come from?

A

Higher brain centers and peripheral and central chemoreceptors

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11
Q

For inspiration, how are the DRG and the VRG connected to the phrenic nerve and the spinal nerves?

A

Spinal respiratory motoneurons

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12
Q

For expiration, how is the VRG connected to spinal nerves?

A

Spinal respiratory motoneurons

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13
Q

What innervates the diaphragm?

A

Phrenic nerve

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14
Q

What innervates the intercostal muscles and the abdominal muscles?

A

Spinal nerves

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15
Q

During eupnea, when is action potential frequency the highest?

A

During inspiration

16
Q

Describe expiration action potentials during eupnea:

A

Occur, but infrequently because expiration is passive.

17
Q

During hypernea, where are the two peak Action potential frequencies seen?

A

1- during end inspiration in the phrenic or intercostal muscles
2- during end expiration in the abdominal or internal intercostals

18
Q

What is the Hering- Breuer inflation reflex?

A

An inspirations stopping reflex mediated through the slowly adapting pulmonary stretch receptors via Vagal afferents and phrenic efferents

19
Q

I’m humans, when is the Hering- Breuer inflation reflex important?

A

During periodic deep breaths, during exercise, and during COPD

20
Q

Describe kussmaul breathing

A

Deep and labored desperate and gasping breathing associated with severe metabolic acidosis.