autonomic nervous system II Flashcards
once a somatic neuron release ACh, what type of nicotenic receptor does it bind to?
N1
once a parasymp or sym neuron releases ACh, what type of receptor does it bind to?
N2
what is the N2 receptor antagonist?
hexamethonium
what is the N1 receptor antagonist?
d-tubocurarine
in parasympathetic neurons what is the receptor type?
muscarinic cholinergic
what is atropine?
a general muscaronic cholinergic receptor antagonist
muscarinic cholinergic receptors M1, M3 & M5 linked to?
activation of PLC, increased intracellular calcium and DAG
muscarinic cholinergic receptors M2 & M4 linked to?
inhibition of adenylyl cyclase and decreased cAMP generation
in regards to parasymp control, what does cranial nerve 3 do?
pupillary constriction
in regards to parasymp control, what does cranial nerve 7 do?
lacrmal gland and nasal mucosal secretions
also salivary glands
in regards to parasymp control, what does cranial nerve 9 do?
salivary glands
in regards to parasymp control, what does cranial nerve 10 do?
GI paralysis/increased motility and sphincter relaxation, bronchial constriction, decreased HR
in regards to parasymp control, what does the pelvic splechnics do?
relax ureter and sphincter in conjunction with contraction of the detrusor muscle during urination, rectal emptying and penile erection
where does the vagus originate?
dorsal motor nucleus and in some of the nuclus ambiguus (where there is also IX)
what are the 4 parasymp pre gang fibers originating in the brain stem?
nerve III (ocuolomotor) nerve VII (facial) nerve IX (glossopharyngeal) nerve X (vagus)