Nervous System Intro Flashcards
1
Q
Name the 4 major ions and where they are in terms of RMP
A
Na - outside
Cl- outside
K- inside
A- large anions inside stuck too large to move
2
Q
What are the 4 monoamine NTs
A
Nadrenaline
Dopamine
5HT - serotonin
3
Q
Name the amino acid NTs
A
Glutamate - +ve
Gaba - -ve
4
Q
How are NTs synthesised
A
Via enzymes which use precursors at the pre synaptic axon terminal
5
Q
How is dopamine produced
A
Via tyrosine precursor
Tyrosine and dopa hydroxylase enzymes
6
Q
What do vesicles protect NTs from
A
Metabolic enzymes
7
Q
What is the channel called which has GPCR that ach binds to to cause K+ influx eg at san
A
GIRK muscarinic receptor