nature of antigens Flashcards
refers to the substances that reacts with antibody or sensitized t cells
a. Antigens
b. Immunogen
c. epitopes
d. nota
antigens
- reacts with antibody or sensitized T cells
- and may not be able to evoke an immune response in the first place
immunogens
- capable in inducing an immune response
epitopes
- key portion of immunogen
substance that is capable of inducing an immune response
a. Antigens
b. Immunogen
c. epitopes
d. nota
antigens
- reacts with antibody or sensitized T cells
- and may not be able to evoke an immune response in the first place
immunogens
- capable in inducing an immune response
epitopes
- key portion of immunogen
most immunogenic in chemical composition of immunogen
a. protein
b. carbohydrates
c. nucleic acid
d. lipids
chemical composition and complexity of immunogen
protein
- most immunogenic
carbohydrates
- 2nd immunogenic
lipids, and nucleic acid
-least immunogenic/ non immunogenic
which of the following is the order of immunogenicity
a. protein> lipid> carbohydrtaes
b. protein > lipopolysaccharides > lipid and nucleic acid
c. protein > nucleic acid > lipopolysaccharides> lipid
order of immunogenicity
protein > lipopolysaccahride > lipid and nucleic acid
able to distinguish self from non self
a. antigens
b. epitopes
c. foreignness
d. nota
foreignness
- able to distinguish self from non self
- those substances recognized as non self are immunogenic
antigen of the same individual
a. autoantigen
b. alloantigen
c. heteroantigen
d. heterophile antigens
autoantigen
- same individual
alloantigen
- antigen from different individual but the same spp
heteroantigen
- antigen from two different spp
heterophile antigens
- they are heteroantigen that exist in unrelated plants and animals but either identical or closely related in structure
part of antibody that binds to the antigenic determinant site
a. paratope
b. epitope
c. immunogen
d. aota
epitope
- part of antigen / immunogen that BINDS TO PARATOPE OF THE ANTIBODY
paratope
- binds to ANTIGENIC DETERMINANT SITE
substance that are to small to recognize by themselves
a. epitope
b. immunogen
c. hapten
d. adjuvants
immunogens
- capable in inducing an immune response
epitopes
- key portion of immunogen
hapten
- too small to recognized by themselves but if they are complexed to larger molecules they are able to stimulate an immune response
substance with immunogen that increases the immune response
a. epitope
b. immunogen
c. hapten
d. adjuvants
immunogens
- capable in inducing an immune response
epitopes
- key portion of immunogen
hapten
- too small to recognized by themselves but if they are complexed to larger molecules they are able to stimulate an immune response
adjuvants
- administered with an immunogen that increases the immune response
major function is to bring or present antigens in the body to the surface of recognition of T cells
a. epitope
b. MHC
c. hapten
d. adjuvants
MAJOR HISTOCOMPATIBILITY COMPLEX
which of the 3 class of MHC has a chain structure b2 - microglobin
a. class I b, class II c. class III
class I
which of the 3 class of MHC has a nature of peptide binding cleft closed at both ends
a. class I b, class II c. class III
class I
present antibody on MHC class II
a. CD4
b. CD8
c. CD19
d. nota
mhc class 1 - CD 8
mhc class II - CD 4