nature of antigens Flashcards

1
Q

refers to the substances that reacts with antibody or sensitized t cells

a. Antigens
b. Immunogen
c. epitopes
d. nota

A

antigens

  • reacts with antibody or sensitized T cells
  • and may not be able to evoke an immune response in the first place

immunogens
- capable in inducing an immune response

epitopes
- key portion of immunogen

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2
Q

substance that is capable of inducing an immune response

a. Antigens
b. Immunogen
c. epitopes
d. nota

A

antigens

  • reacts with antibody or sensitized T cells
  • and may not be able to evoke an immune response in the first place

immunogens
- capable in inducing an immune response

epitopes
- key portion of immunogen

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3
Q

most immunogenic in chemical composition of immunogen

a. protein
b. carbohydrates
c. nucleic acid
d. lipids

A

chemical composition and complexity of immunogen

protein
- most immunogenic

carbohydrates
- 2nd immunogenic

lipids, and nucleic acid
-least immunogenic/ non immunogenic

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4
Q

which of the following is the order of immunogenicity

a. protein> lipid> carbohydrtaes
b. protein > lipopolysaccharides > lipid and nucleic acid
c. protein > nucleic acid > lipopolysaccharides> lipid

A

order of immunogenicity

protein > lipopolysaccahride > lipid and nucleic acid

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5
Q

able to distinguish self from non self

a. antigens
b. epitopes
c. foreignness
d. nota

A

foreignness

  • able to distinguish self from non self
  • those substances recognized as non self are immunogenic
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6
Q

antigen of the same individual

a. autoantigen
b. alloantigen
c. heteroantigen
d. heterophile antigens

A

autoantigen
- same individual

alloantigen
- antigen from different individual but the same spp

heteroantigen
- antigen from two different spp

heterophile antigens
- they are heteroantigen that exist in unrelated plants and animals but either identical or closely related in structure

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7
Q

part of antibody that binds to the antigenic determinant site

a. paratope
b. epitope
c. immunogen
d. aota

A

epitope
- part of antigen / immunogen that BINDS TO PARATOPE OF THE ANTIBODY

paratope
- binds to ANTIGENIC DETERMINANT SITE

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8
Q

substance that are to small to recognize by themselves

a. epitope
b. immunogen
c. hapten
d. adjuvants

A

immunogens
- capable in inducing an immune response

epitopes
- key portion of immunogen

hapten
- too small to recognized by themselves but if they are complexed to larger molecules they are able to stimulate an immune response

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9
Q

substance with immunogen that increases the immune response

a. epitope
b. immunogen
c. hapten
d. adjuvants

A

immunogens
- capable in inducing an immune response

epitopes
- key portion of immunogen

hapten
- too small to recognized by themselves but if they are complexed to larger molecules they are able to stimulate an immune response

adjuvants
- administered with an immunogen that increases the immune response

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10
Q

major function is to bring or present antigens in the body to the surface of recognition of T cells

a. epitope
b. MHC
c. hapten
d. adjuvants

A

MAJOR HISTOCOMPATIBILITY COMPLEX

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11
Q

which of the 3 class of MHC has a chain structure b2 - microglobin

a. class I
b, class II
c. class III
A

class I

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12
Q

which of the 3 class of MHC has a nature of peptide binding cleft closed at both ends

a. class I
b, class II
c. class III
A

class I

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13
Q

present antibody on MHC class II

a. CD4
b. CD8
c. CD19
d. nota

A
mhc class 1
  - CD 8
mhc class II
  - CD 4
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