introduction Flashcards
this is fresh material taken from a skin lesion of a person recovering from smallpox was subcutaneously injected with lancet in to the arm or leg of a nonimmune person
a. attenuation
b. variolation
c. vaccine
d. aota
Variolation
- method:
: scratching the skin
: applying pulverized powder from a smallpox scab
-taken from a skin lesion of a person recovering from smallpox was subcutaneously injected with lancet in to the arm or leg of a nonimmune person
VACCINIA pertains to
a. cowpox
b. smallpox
c. Alastrim
vaccinia - cowpox
variola major - smallpox
variola minor - alastrim
variola minor pertains
a. cowpox
b. smallpox
c. Alastrim
vaccinia - cowpox
{ c=cow)
variola major - smallpox
{major- small}
variola minor - alastrim
{minor - ala}
which of the following is the advantage of ORAL VACCINES
a. recognizing and response to foreign antigens
b. stimulate the mucosa immunity
c. humoral antibody production
d. cell mediated response
oral vaccines have an additional advantages
- stimulate the mucosal immunity
- humoral antibody production
- cell mediated response
Live pathogens that have been weakened by growth under modified culture condition
a. variolation
b. toxoids
c. attenuated
d. inactivated
attenuated
- WEAKEND
- advantages : induces both humoral and cell mediated immunity
: effective in inducing immunity after a single dose
what vaccines is killed microorganisms
a. variolation
b. toxoids
c. attenuated
d. inactivated
inactivated
- KILLED microorganisms
- advantages : can be safely be given in immunocompromised patients
what conventional vaccines has a composition of protein produced by genetically modified nonpathogenic bacteria, yeast, or other cells
a. variolation
b. recombinant antigen
c. attenuated
d. inactivated
recombinant antigen
- protein produced by modified non pathogenic bacteria , yeast or other cells
- examples: HEPA B, HUMAN PAPILLOMA VIRUS (HPV)
what vaccine is yellow fever
a. purified components
b. toxoids
c. attenuated
d. inactivated
attenueated
-examples:
BCG
TYPHOID FEVER
ORAL POLIO
MEASLES
MUMPS
GERMAN MEASLES
CHICKEN POX
YELLOW FEVER
ROTA VIRUSwhat vaccine is rota virus
a. purified components
b. toxoids
c. attenuated
d. inactivated
attenueated
-examples:
BCG
TYPHOID FEVER
ORAL POLIO
MEASLES
MUMPS
GERMAN MEASLES
CHICKEN POX
YELLOW FEVER
ROTA VIRUSwhat vaccine is german measles
a. purified components
b. toxoids
c. attenuated
d. inactivated
attenueated
-examples:
BCG
TYPHOID FEVER
ORAL POLIO
MEASLES
MUMPS
GERMAN MEASLES
CHICKEN POX
YELLOW FEVER
ROTA VIRUSwhat vaccine is Streptococcus pneumoniae
a. purified components
b. toxoids
c. attenuated
d. polysaccharides
polysaccharides
- examples:
Streptococcus pneumoniae
Neisseria meningitis
Haemophillus influenzae b(HIB)
what vaccine is Hepatitis A
a. purified components
b. toxoids
c. attenuated
d. inactivated
inactivated
- example:
: hepatitis A
intramascular polio (salk)
influenza
rabieswhat vaccine is diptheria
a. purified components
b. toxoids
c. attenuated
d. inactivated
toxoids
- example
diptheria
tetanus
puried components
example
pertussis (whooping cough)
because of the broad immunity induced by live , attenuated vaccines , they generally induce an EFFECTIVE IMMUNE REPONSE ______________
a. in 1st dose
b. after a single dose
c. non of the above
because of the broad immunity induced by live , attenuated vaccines , they generally induce an EFFECTIVE IMMUNE REPONSE AFTER A SINGLE DOSE
who develop polio vaccine
a. Ellie metchnikoff
b. louis pasteur
c. salk, sabin
d. reed
a. Ellie metchnikoff
- PHAGOCYTOSIS
b. louis pasteur
- live , attenuated chicken cholera and anthrax vaccines
c. salk (inject) , sabin (oral)
- polio vaccine
d. reed
- vaccine against yellow fever
father of immunology
a. Ellie metchnikoff
b. louis pasteur
c. salk, sabin
d. reed
a. Ellie metchnikoff
- PHAGOCYTOSIS
b. louis pasteur
- live , attenuated chicken cholera and anthrax vaccines
- father of immunology
c. salk (inject) , sabin (oral)
- polio vaccine
d. reed
- vaccine against yellow fever
demostration of cutaneous (delayed type) hypersensitivity
a. koch
b. louis pasteur
c. portier , richet
d. ehrlich
Koch
- cutaneous (DELAYED TYPE) hypersensitivity
Louis Pasteur
- live attenuated vaccine
Portier, Richet
- IMMEDIATE hypersensitivity anaphylaxis
Ehrlich
- ANTIBODY FORMATION theory
development of human papilloma virus
a. frazer
b. kohler
c. burnet
d. marrack
Frazer (2005)
- human papilloma virus
Kohler (1975)
- FIRST MONOclonal antibody
BUrnet (1955)
- clonal SELECTION THEORY
Marrack (1938)
- HYPOTHESIS of antigen - antibody BINDING
Who discovered complement
a. susumu tonegawa
b. robert kaus
c. jules bordet
d, emil von behring
Susumu Tonegawa
- antibodies with different specificities
Robert Kaus
- discovered PRECIPITINS
(RP) / santa KlAUS every PRE Christmas
JULES BORDET
- complement
- si Jules icomplement mo naman
Emil Von Behring
- 1st immunology nobel prize for his work in SERUM THERAPY
What year does the T cell receptor gene discovered
a. 1972
b. 1984
c. 2005
d. 1901
1972
- kohler - first monoclonal antibodies
1984
- DISCOVERYOF T CELL RECEPTOR GENE
2005
- Development of human papillomavirus
1901
- emil von behring - serum therapy
vaccine is a form of _______
a. phosphocholine
b. immunoprophylaxis
c. cross immunity
vaccine is a form of IMMUNOPROPHYLAXIS or the prevention of disease through immnunization
phospholine - CRP
cross immunity - Edward Jenner
