introduction Flashcards

1
Q

this is fresh material taken from a skin lesion of a person recovering from smallpox was subcutaneously injected with lancet in to the arm or leg of a nonimmune person

a. attenuation
b. variolation
c. vaccine
d. aota

A

Variolation
- method:
: scratching the skin
: applying pulverized powder from a smallpox scab

-taken from a skin lesion of a person recovering from smallpox was subcutaneously injected with lancet in to the arm or leg of a nonimmune person

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2
Q

VACCINIA pertains to

a. cowpox
b. smallpox
c. Alastrim

A

vaccinia - cowpox

variola major - smallpox

variola minor - alastrim

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3
Q

variola minor pertains

a. cowpox
b. smallpox
c. Alastrim

A

vaccinia - cowpox
{ c=cow)

variola major - smallpox
{major- small}

variola minor - alastrim
{minor - ala}

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4
Q

which of the following is the advantage of ORAL VACCINES

a. recognizing and response to foreign antigens
b. stimulate the mucosa immunity
c. humoral antibody production
d. cell mediated response

A

oral vaccines have an additional advantages

  • stimulate the mucosal immunity
  • humoral antibody production
  • cell mediated response
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5
Q

Live pathogens that have been weakened by growth under modified culture condition

a. variolation
b. toxoids
c. attenuated
d. inactivated

A

attenuated
- WEAKEND

  • advantages : induces both humoral and cell mediated immunity
    : effective in inducing immunity after a single dose
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6
Q

what vaccines is killed microorganisms

a. variolation
b. toxoids
c. attenuated
d. inactivated

A

inactivated
- KILLED microorganisms

  • advantages : can be safely be given in immunocompromised patients
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7
Q

what conventional vaccines has a composition of protein produced by genetically modified nonpathogenic bacteria, yeast, or other cells

a. variolation
b. recombinant antigen
c. attenuated
d. inactivated

A

recombinant antigen
- protein produced by modified non pathogenic bacteria , yeast or other cells

  • examples: HEPA B, HUMAN PAPILLOMA VIRUS (HPV)
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8
Q

what vaccine is yellow fever

a. purified components
b. toxoids
c. attenuated
d. inactivated

A
attenueated
 -examples:
                        BCG
                        TYPHOID FEVER
                         ORAL POLIO
                         MEASLES
                         MUMPS
                        GERMAN MEASLES
                        CHICKEN POX
                         YELLOW FEVER
                         ROTA VIRUS
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9
Q

what vaccine is rota virus

a. purified components
b. toxoids
c. attenuated
d. inactivated

A
attenueated
 -examples:
                        BCG
                        TYPHOID FEVER
                         ORAL POLIO
                         MEASLES
                         MUMPS
                        GERMAN MEASLES
                        CHICKEN POX
                         YELLOW FEVER
                         ROTA VIRUS
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10
Q

what vaccine is german measles

a. purified components
b. toxoids
c. attenuated
d. inactivated

A
attenueated
 -examples:
                        BCG
                        TYPHOID FEVER
                         ORAL POLIO
                         MEASLES
                         MUMPS
                        GERMAN MEASLES
                        CHICKEN POX
                         YELLOW FEVER
                         ROTA VIRUS
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11
Q

what vaccine is Streptococcus pneumoniae

a. purified components
b. toxoids
c. attenuated
d. polysaccharides

A

polysaccharides
- examples:

                    Streptococcus pneumoniae
                    Neisseria meningitis
                    Haemophillus influenzae b(HIB)
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12
Q

what vaccine is Hepatitis A

a. purified components
b. toxoids
c. attenuated
d. inactivated

A
inactivated
  - example:
     : hepatitis A
       intramascular polio (salk)
       influenza
        rabies
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13
Q

what vaccine is diptheria

a. purified components
b. toxoids
c. attenuated
d. inactivated

A

toxoids
- example
diptheria
tetanus

puried components
example
pertussis (whooping cough)

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14
Q

because of the broad immunity induced by live , attenuated vaccines , they generally induce an EFFECTIVE IMMUNE REPONSE ______________

a. in 1st dose
b. after a single dose
c. non of the above

A

because of the broad immunity induced by live , attenuated vaccines , they generally induce an EFFECTIVE IMMUNE REPONSE AFTER A SINGLE DOSE

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15
Q

who develop polio vaccine

a. Ellie metchnikoff
b. louis pasteur
c. salk, sabin
d. reed

A

a. Ellie metchnikoff
- PHAGOCYTOSIS

b. louis pasteur
- live , attenuated chicken cholera and anthrax vaccines

c. salk (inject) , sabin (oral)
- polio vaccine

d. reed
- vaccine against yellow fever

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16
Q

father of immunology

a. Ellie metchnikoff
b. louis pasteur
c. salk, sabin
d. reed

A

a. Ellie metchnikoff
- PHAGOCYTOSIS

b. louis pasteur
- live , attenuated chicken cholera and anthrax vaccines
- father of immunology

c. salk (inject) , sabin (oral)
- polio vaccine

d. reed
- vaccine against yellow fever

17
Q

demostration of cutaneous (delayed type) hypersensitivity

a. koch
b. louis pasteur
c. portier , richet
d. ehrlich

A

Koch
- cutaneous (DELAYED TYPE) hypersensitivity

Louis Pasteur
- live attenuated vaccine

Portier, Richet
- IMMEDIATE hypersensitivity anaphylaxis

Ehrlich
- ANTIBODY FORMATION theory

18
Q

development of human papilloma virus

a. frazer
b. kohler
c. burnet
d. marrack

A

Frazer (2005)
- human papilloma virus

Kohler (1975)
- FIRST MONOclonal antibody

BUrnet (1955)
- clonal SELECTION THEORY

Marrack (1938)
- HYPOTHESIS of antigen - antibody BINDING

19
Q

Who discovered complement

a. susumu tonegawa
b. robert kaus
c. jules bordet
d, emil von behring

A

Susumu Tonegawa
- antibodies with different specificities

Robert Kaus
- discovered PRECIPITINS
(RP) / santa KlAUS every PRE Christmas

JULES BORDET

  • complement
  • si Jules icomplement mo naman

Emil Von Behring
- 1st immunology nobel prize for his work in SERUM THERAPY

20
Q

What year does the T cell receptor gene discovered

a. 1972
b. 1984
c. 2005
d. 1901

A

1972
- kohler - first monoclonal antibodies

1984
- DISCOVERYOF T CELL RECEPTOR GENE

2005
- Development of human papillomavirus

1901
- emil von behring - serum therapy

21
Q

vaccine is a form of _______

a. phosphocholine
b. immunoprophylaxis
c. cross immunity

A

vaccine is a form of IMMUNOPROPHYLAXIS or the prevention of disease through immnunization

phospholine - CRP

cross immunity - Edward Jenner