natural immunity .. Flashcards

1
Q

which of the three groups of PRRs is a molecule that circulates in blood and lymph

a. secreted prr
b. phagocystosis prr
c. toll like receptors

A

secreted PRRs

  • is a molecule that circulate in blood and lymph
  • circulating proteins BINDS TO PAMPs on the surface of pathogens
  • it triggers the complement cascade, leading to opsonization of pathogen and speedy phagocytosis
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2
Q

which of the three groups of PRRs can trigger the complement cascade

a. secreted prr
b. phagocystosis prr
c. toll like receptors

A

secreted PRRs

  • is a molecule that circulate in blood and lymph
  • circulating proteins BINDS TO PAMPs on the surface of pathogens
  • it triggers the complement cascade, leading to opsonization of pathogen and speedy phagocytosis
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3
Q

which of the three groups of PRRs initiates signal leading release of effector molecules

a. secreted prr
b. phagocystosis prr
c. toll like receptors

A

Phagocytosis receptors

  • is cell surface receptors that bind the pathogen
  • initiiating a signal leading to the release of effectro molecules
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4
Q

_________ have cell surface receptors that recognize PAMP’s containing mannose

a. monocyte
b. neutrophil
c. macrophages
d. leukocytes

A

Macrophages

- have cell surface receptors that recognize PAMP’s containing mannose

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5
Q

which of the three groups of PRRs are set of transmembrane receptors that recognize different types of PAMPs

a. secreted prr
b. phagocystosis prr
c. toll like receptors

A

toll like receptors

- it can recognize different types of PAMPs

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6
Q

___ recognizes teichoic acid and peptidoglycan that can be found in gram positive bacteria

a. TLR 1
B. TLR 2
C. TLR 5
D. TLR 4

A

TLR 2
- recognizes teichoic acid and peptidoglycan that can be found in gram positive bacteria

TLR 4
- LIPOPOLYSACCHARIDE can be found in gram negative bacteria

tlr 1
- lipoprotein - mycobacteria

tlr 5
- bacterial flagellin

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7
Q

to localize and eradicate the irritant and repair the surrounding tissue

a. phagocytosis
b. acute phase reactants
c. inflammation
d. aota

A

INFLAMMATION

- primary objective of inflammation is to localize and eradicate the irritant and repair the surrounding tissue

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8
Q

______ is the primary inflammatory response

a. phagocytosis
b. dipedesis
c. vasodilation

A

vasodilation

- primary inflammatory response

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9
Q

is the process by which cells are capable of moving from circulating blood to the tissue by squeezing through the wall of blood vessel

a. phagocytosis
b. dipedesis
c. vasodilation

A

Diapedesis

  • cells are capable of moving
  • squeezing through the wall of blood vessel
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10
Q

which of the following cardinal signs can cause pain

a. rubor
b. dolor
c. calor
d. tumor

A
rubor  - redness
dolor  - pain
calor  - heat
tumor  - swelling
functio laesa  - loss or dimished function
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11
Q

which of the cardinal signs of inflammation is the 1st sign

a. rubor
b. dolor
c. calor
d. tumor

A
rubor  - redness  (1st sign)
dolor  - pain
calor  - heat
tumor  - swelling
functio laesa  - loss or dimished function
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12
Q

what is the predominant cell found in chronic inflammation

a. monocytes
b. mast cell
c. dendritic cell
d. neutrophil

A

MACROPHAGE / MONOCYTES
- predominant cells in chronic

neutrophil
- predominant in acute inflammation

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