immunodeficiencies

Question 1

which of the following deficiencies belongs to humoral/ b cell deficiency

a. selective IgA
b. bruton’s agammaglobinemia
c. common variable immunodeficiency
d. transient hypogammaglobinemia
e. nota
d. aota

Answer 1

humoral immunity / b cell deficiency

a. selective IgA
b. bruton’s agammaglobinemia
c. common variable immunodeficiency
d. transient hypogammaglobinemia

answer: aota

Question 2

which of the following deficiencies belongs to cellular immunity / t cell deficiency

a. selective IgA
b. bruton’s agammaglobinemia
c. di george anomaly
d. purine nucleotidase phosphorylase deficiency

Answer 2

cellular immunity / t cell deficiency

1. di george anomaly
2. PNP (purine nucleotidase phophorylase deficiency)

Question 3

which of the following deficiencies belongs to combined t and b cell deficiency

a. selective IgA
b. scid
c. wiskot - aldrich syndrome
d. ataxia telangiectasia
e. nota

Answer 3

combined t and b cell deficiency

1. scid (severe combined immunodeficiency)
2. wiskott - aldrich syndrome’
3. ataxia telangiectasia

Question 4

this deficiency affects the purine metabolism

a. di george anomaly
b. PNP deficiency
c. wiskott aldrich
d. selective IgA

Answer 4

purine nucloeside phosphorylase deficiency

• affects enzyme involved in the metabolism of purines
• t cell progressively decreases

Question 5

a development of 3rd and 4th pharyngeal pouches that affects thymic development

a. di george anomaly
b. PNP deficiency
c. wiskott aldrich
d. selective IgA

Answer 5

di george anomaly

- a development of 3rd and 4th pharyngeal pouches that affects thymic development

Question 6

triad of eczema, thrombocytopenia and immunodeficiency

a. di george anomaly
b. PNP deficiency
c. wiskott aldrich
d. selective IgA

Answer 6

wiskott aldrich

Question 7

most common immunodeficiency

a. di george anomaly
b. PNP deficiency
c. wiskott aldrich
d. selective IgA

Answer 7

selective IgA

Question 8

deficiency or lack of immunoglobulins

a. di george anomaly
b. PNP deficiency
c. x-linked agammaglobinemia
d. selective IgA

Answer 8

x - linked agammaglobinemia / bruton’s agammaglobinemia

• lack of circulating CD19 + b cells
• exhibit a deficiency or lack of immunoglobulins of all classes