HYPERSENSITIVITY

Question 1

HEIGHTENED STATE OF IMMUNE RESPONSE

a. antibodies
b. interleukin
c. MHC
d hypersensitivity

Answer 1

hypersensitivity
- defined as : HEIGHTENED STATE OF IMMUNE RESPONSE

• exaggerated response to a harmless antigen that results in injury to the tissue, disease or even death

Question 2

which of these are effector cells of type II hypersensitivity

a. basophil, mast cell
b. rbc, platelet, wbc
c. host tissue cell
d. macrophages , t cells

Answer 2

type I
-basophil, mast cell

type II
- rbc, platelet, wbc

type III
- host tissue cell

type IV
- macrophages , t cells

Question 3

which of these are effector cells of type IV hypersensitivity

a. basophil, mast cell
b. rbc, platelet, wbc
c. host tissue cell
d. macrophages , t cells

Answer 3

type I
-basophil, mast cell

type II
- rbc, platelet, wbc

type III
- host tissue cell

type IV
- macrophages , t cells

Question 4

antigen
soluble: autologous or heterologous

a. type I
B,. TYPE II
C. TYPE III
D, TYPE IV

Answer 4

ANTIGEN :

TYPE 1
- HETEROLOGOUS

TYPE II
- CELL SURFACE; AUTOLOGOUS OR HETEROLOGOUS

TYEP III
- SOLUBLE; AUTOLOGOUS OR HETEROLOGOUS

TYPE IV
- AUTOLOGOUS OR HETEROLOGOUS

Question 5

which of the following hypersensitivity does pneumonitis belongs

a. type I
B,. TYPE II
C. TYPE III
D, TYPE IV

Answer 5

type IV

• contact dermatitis
• tuberculin/ ppd test
• pneumonitis
• m,antoux
• anergy skin test
• hypersensitivity pneumonitis (farmers lung)
• type 1 dm
• gvhd

Question 6

which of the following hypersensitivity does iaha
belongs

a. type I
B,. TYPE II
C. TYPE III
D, TYPE IV

Answer 6

type II

• transfusion rx
• aiha
• hdn
• good pasteurs syndrome
• myasthenia gravis
• graves disease
• itp

Question 7

which of the following hypersensitivity does neoplastic diseases belongs

a. type I
B,. TYPE II
C. TYPE III
D, TYPE IV

Answer 7

type III

• serum sickness
• arthus reaction
• sle
• rheumatoid arthritis
• post streptococccal glomerulonephritis assoc in sle
• other autoimmune disorders
• neoplastic disease

Question 8

which of the hypersensitivity is known as anaphylactic

a. type I
B,. TYPE II
C. TYPE III
D, TYPE IV

Answer 8

type I
- anaphylactic

type II
- cytotoxic

type III
- immune complex

type IV
- delayed or cell mediated

Question 9

what test to perform on HTR

a. rist
b. rast
c. dat
d. latex agglution

Answer 9

type II test
I. Direct antiglobulin test / coombs test
(test for HTR, HDN AND AUTO IMMUNE HEMOLYTIC ANEMIA)

II. direct fluorecence examination

III indirect fluorescence immunoassay

Question 10

a competitive test for total ige

a. rist
b. rast
c. dat
d. latex agglution

Answer 10

type 1 test
I. skin test / patch test
a. cutaneous
b . intradermal

II. in vitro immunoassay

a. RIST - competative Ria test for TOTAL IGE
b. RaST - non competative ria test for SPECIFIC IgE

Question 11

test for renal tissue biopsy for Good Pasteur syndrome

a. rist
b. rast
c. dat
d. direct fluorescence examination

Answer 11

type II test
I. Direct antiglobulin test / coombs test
(test for HTR, HDN AND AUTO IMMUNE HEMOLYTIC ANEMIA)

II. direct fluorecence examination
- test for renal tissue biopsy for Good Pasteur syndrome

III indirect fluorescence immunoassay
- auto antibody detection

Question 12

gold standard test for contact dermatitis

a. RIST
b. RAST
c. PPD
d. patch

Answer 12

type IV
I. PATCH TEST
- gold standard tets for contact dermatitis

II. MANTOUX/ TUBERCULIN / PPD

Question 13

THIS TEST IS DONE IN PATIENT THAT IS FREE OF SYMPTOMS

a. RIST
b. RAST
c. PPD
d. patch

Answer 13

type IV
I. PATCH TEST
- gold standard tets for contact dermatitis
- DONE IN PATIENT THAT IS FREE OF SYMPTOMS

II. MANTOUX/ TUBERCULIN / PPD