NA 2 Flashcards
Low levels of serotonin
Mood disorders like anxiety
Lack of acetylcholine and glutamate
Alzheimer’s disease
Pleasure, addiction, movement, and motivation.
Repeated behaviors lead to dopamine release
dopamine
Area where neurotransmitters are released from presynaptic terminals to the receptors at the postsynaptic membrane
Synaptic cleft/junction
Starting point
Connected to the soma
Accept information from other neurons
dendrites
peptides
opioids, endorphins, somatostatin, oxytocin, vasopressin
Usually found in invertebrates
Single axon
Unipolar
no ribosomes
Smooth ER
Command center of the cell
Nucleus
Can affect a number of neurons at the same time and influence the effects of other chemical messengers
Modulatory neurotransmitter
has ribosomes
Rough ER
Transport electrical impulses to terminal knobs
Axon
Lowered GABA levels
Epilepsy and Huntington’s disease
Monoamines
dopamine, noradrenaline, adrenaline, histamine, serotonin
Too little dopamine in the brain’s motor areas
Parkinson’s disease
Aka plasma membrane
Lipid bilayer - thin polar membrane composed of two layered arrangement of phosphate and lipid molecules
Semipermeable
cell membrane
Ligand or chemical activated ion channels
Neurotransmitter receptors
Single elongate process with cell body at one side
Pseudounipolar
Excitatory neurotransmitters
adrenaline/Epinephrine
Noradrenaline/norepinephrine
glutamate
Histamine
aspartate
amino acids
GABA, glutamate, glycine, D-serine, Aspartate
Long tail like branching
may be single or multiple
Pre-synaptic function
Axon
smallest type of neuroglia
Microglia
postsynaptic function
dendrities
Creates cerebrospinal fluid
Ependymal cells
Thick section of the cell body that attaches to the initial segment
Axon hillock
Presynaptic
Negative feedback
autoreceptors
intercellular communication
chemical
One axon but several dendrites to form a pyramid shape
Largest neuron
Found in cortex
Pyramidal neurons
Creates myelin sheath for PNS
Schwann cells
Receives transmission
Dendrites
Cell membrane of the cells in the PNS
Neurolema
Two extensions extending from the cell body
One end is axon other is dendrite
Found in retina and nose and eye function
Bipolar neurons
More than two processes but axons cannot be distinguished from dendrite
Anaxonic neurons
Free movement
Scavenger role in phagocytosis (type of endocytosis; ingesting particles)
Fountains of microglia
Prevalent during the development and reshaping the brain
No properties of inflammation and antigen-presenting
Ameboid microglia
Terminal end of the axon
Terminal knob
Structural framework of the nerve cell
Cytoskeleton
Euphoria
Released during exercise, excitement, sex, reduce pain
Endorphins
presynaptic function
axon
Organelles that can contain chemicals such as neurotransmitters or digestive enzymes
Vesicle/ Vacuole
Major component of cytoskeleton
Where neurotransmitter can travel from soma to terminal axon
Microtubules
Learning
Thought, learning and memory, attention and awakening
Activates muscle action in the body
acetylcholine
Creates myelin sheath for the CNS
Oligodendrocytes
Excessive amounts of dopamine in the mesolimbic pathway of the brain
Schizophrenia
Part of the microtubule that helps in stability and growth
Microfilament
Usually terminal knob of axon
Presynaptic
Powerhouse of the cell
Provide energy
Mitochondria
Pinakamaraming glial cell
Creates fibers and nerves
Kapit sa myelin sheath
Sticks neuron to blood vessel
Astrocyte
Inhibitory neurotransmitters
GABA
Glycine
Serotonin
The gap connection between nerve cells
Synapse
Both exhibitory and inhibitory neurotransmitters
Acetylcholine
Norepinephrine
Dopamine
Produces and assemble cell ribosome
Nucleolus
Have inhibitory effects, decrease likelihood that the neuron will fire an action
Inhibitory neurotransmitters
Branching appendages of the nerve cell
Post synaptic function
Dendrites
Packaging (neurotransmitters) organelles of the cell (vesicles
Golgi complex/bodies
Pinakamarami
Acts as a glue
Aka neuroglia
Glial cells
others nt
acetylcholine, adenosine, nitric acid
End point of axon where synapse is located
Terminal knobs
Mood
Contributes to wellbeing and happiness
Helps with sleep cycle and digestive regulation
Affected by exercise and light exposure
serotonin
Have excitatory effects, increase likelihood that the neuron will fire an action potential
excitatory nt
Multiple dendrites that fan out of the cell body
Inhibitory neurons (release neurotransmitters to stop other neurons from firing)
Purkinje neurons
Bundle of neurons with the same function that glial cells connect
Nerves
Main control system of the cell
Accepts or rejects signals
command center of cell
nucleus
Linked to noradrenaline
Mood disorders like manic depression, anxiety, and impaired sleep cycle
Fully active phagocytic form
Inflammatory and neurotoxic
Thickening and retraction of branches
Antigen-presenting
Neuro-inflammation
Fully active phagocytic form
Activated microglia
Memory
Most common neurotransmitter
Learning and memory, regulates development and creation of nerve contacts
Glutamate
Glues to specific organs
Satellite cells
Vesicles containing digestive enzyme, use oxidative reaction for digestion
Peroxisome
Attaches to the axon hillock
Initial segment
Creates myelin sheath for CNS
Oligodendrocytes
Fight or flight
Produced in stressful situations
Increases heart rate and blood flow leading to physical boost and heightened awareness
adrenaline
Concentration, affects attentions and responding actions
Contracts blood vessels, increasing blood flow
noradrenaline
The gap between the synapse from the presynaptic neuron towards the postsynaptic neuron
Synaptic cleft
Space between the terminal knob and dendrite
The gap connection between nerve cells
synapse
maintaining g an immunologically stable environment
Active macrophages (type of white blood cell that does phagocytosis)
Long branches and a small cellular body
Prevalent in adulthood brain
Creates stiff connections with brain
Ramified microglia
Single axon with symmetrical dendrites
Most common in CNS
Multipolar neurons
Usually distal membrane appendage of dendrite
Post-synaptic
Cell membrane of the cells in the CNS
Plasma cell membrane
Insulator and bounces the signal
Myelin sheath
An area usually between an axon and a dendrite divided by the synaptic cleft
Synapse
intracellular communication
electric
Creates myelin sheath for the PNS
Schwann’s cells
Cell body; contains the main supporting system of the cell
soma
Calming
Calms firing nerves in CNS
High levels improve focus, low levels cause anxiety
Contributes to motor control and vision
GABA (Gamma-aminobutyric acid)
Vesicle contains digestive enzyme used to break down or remove excess and worn-out cell parts
Lysosome