Muscle Tissue - Quiz 2 Flashcards
What do you call a synapse between a skeletal muscle cell and a motor neuron?
A neuromuscular junction (NMJ)
Where are NMJs usually located?
the midpoint of the muscle fiber
How many NMJ are there per muscle fiber
usually ONE only
How many muscle fibers can a single axon innervate?
up to 3000
What is a nerve and the fibers it innervates called?
a Motor Unit
What are the steps in generating a muscle action potential?
- release of acetylcholine
- activation of acetylcholine receptors
- production of muscle action potential
4, termination of acetylcholine activity
What are the steps in the Sliding Filament Theory?
- action potential
2 release of calcium ions - exposure of myosin binding site
- contraction cycle
- relaxation
What can inhibit muscle contractions?
- rigor mortis
- curare
- acetylcholinesterase inhibitors
- substances affecting release of acetylcholine.
What causes rigor mortis?
Insufficient ATP so myosin heads can’t detach from actin.
What does curare do?
Binds to acetylcholine receptors but doesn’t create an action potential.
What are Sevin and Sarin?
acetylcholinesterase inhibitors.
What is muscle tone?
the firmness of a skeletal muscle in a relaxed state
What are the 2 types of hypertonicity?
spasticity
rigidity
What do skeletal muscles use ATP for?
contraction
active transport pumps