MSK Flashcards
decreased bone quantity with normal quality of bone
osteoporosis
decreased bone quality with softening of the bone in an adult
osteomolacia
soft bones that easily bend in children
rickets
multiple brown cysts in long bones seen in hyperparathyroidism
osteitis fibrosa cystica
another name for osteitis fibrosa cystica
hyperparathyroidism
disordered thickening of bone with deformities in older people
Paget’s disease
alternate name for Paget’s disease
osteitis deformans
possible causative organism in Paget’s disease
paramyxovirus
short person with normal head and trunk but shortened limbs
achondroplasia
severe joint destruction without any pain
Charcot’s joint
recurrent fractures with blue sclera in an infant
osteogenesis imperfecta
blood-borne infection of bone; fever, bone pain, and swelling
osteomyelitis
m/c organism causing osteomyelitis
staphylococcus aureus
bone outgrowth with a cartilage cap; m/c in children
osteochondroma
most common benign bone tumor in the hand
enchondroma
multiple enchondromas
Ollier’s disease
island of dense bone in spine or skull
osteoma
benign metaphyseal bone tumor extending into epiphysis
giant cell tumor
soap-bubble appearance in the shaft extending to metapysis
aneurysmal bone cyst
m/c malignant bone tumor
secondary bone tumors
m/c primary malignant bone tumor
multiple myeloma
m/c primary malignant bone tumor in teens
osteosarcoma
Bence Jones proteins and M spike serum electophoresis
multiple myeloma
punch-out lesions in the skull and hypercalcemia
multiple myeloma
malignant bone tumor with Codman’s triangle on x-ray
osteosarcoma
malignant bone tumor resembling osteomyelitis
Ewings sarcoma
malignant bone tumor with onion-skin appearance on x-ray
Ewings sarcoma
3rd m/c primary malignant bone tumor
chondrosarcoma
malignant bone tumor associated with Paget’s disease
osteosarcoma
seropositive arthritis (Rheumatoid Factor +1)
RA and SLE
pannus formation in a young female with multiple joint pains
RA
Swan neck and boutonniere deformity with Haygarth’s nodes
RA
RA in teens with splenomegaly
Still’s disease
splenomegaly, neutropenia and RA
Felty’s syndrome
young black teen with multiple joint pains and malar rash
SLE
heart valve damage associated with SLE
Libman-Sack’s endocarditis
kidney disease associated with SLE
nephrotic syndrome
dry eyes, dry mouth, and joint pains
Sjogren’s syndrome
type of antibodies in scleroderma
anti-centromere antibodies
Reiter’s syndrome, psoriatic arthritis, AS
seronegative arthritis
multiple small joint pains with chronic silvery skin rash
psoriatic arthritis
LBP and bamboo spine in young male
AS
urethritis, conjunctivitis, and arthritis
Reiter’s synd.
bacterial organisms linked to Reiter’s synd
chlamydia or shigella
heberden’s and bouchard’s nodes in older females
osteoarthritis
big toe joint pain after alcohol binge, uric acid excess, tophi
gout
negatively birefringent needle-shaped crystals in joint
uric acid
tick borne disease with bull’s eye rash and joint pain
lyme disease
diplopia, fatigue and ptosis, middle-aged female, + tensilon test
myashenia gravis
type of antibodies in myasthenia gravis
acetylcholine receptor
associated pathology in myasthenia gravis
thymic pathology
diplopia, fatigue and ptosis, older male, calcium channel antibody
Lambert-Eaton synd
heliotrope rash, swollen eyelids and papules on the knuckles
dermatomyositis
papules on the knuckles seen in dermatomyositis
Gottron’s papules
type of antibodies seen in dermatomyositis
anti-Jo-1 antibodies
muscle weakness, pseudohypertorphic calves, Gower’s sign, males
Duchenne’s dystrophy
defect resulting in Duchene’s muscular dystrophy
dystrophin
less severe form of Duchenn’es
Decker’s muscular dystrophy
progressive peroneal muslce wasting
Charcot-Marie-Tooth syndrome
avascular necrosis of head of femur in young boys
Legg-Calve-Perthes disease
displaced epiphysis of the head of femur in overweight teens
SCFE
pain and stiffness in older females with very high ESR
polymyalgia rheumatica
